Lexiva and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexiva (fosamprenavir calcium) and Ambien (zolpidem tartrate). Common drug interactions include pain among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Lexiva and Ambien. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Lexiva?

Lexiva has active ingredients of fosamprenavir calcium. It is often used in hiv infection. eHealthMe is studying from 1,408 Lexiva users. Check the latest studies of Lexiva.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

On Jul, 11, 2026

17 people who take Lexiva and Ambien together, and have interactions are studied.

What are the common drug interactions of Lexiva and Ambien, by gender? *:

female:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Emotional distress
Hip arthroplasty
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Gout (uric acid crystals building up in the body)
Haematuria (presence of blood in urine)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Joint dislocation (a joint position is changed from normal position)
Neuropathy peripheral (surface nerve damage)
Osteoporosis (bones weak and more likely to break)
Proteinuria (presence of protein in the urine)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

What are the common drug interactions of Lexiva and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Blood calcium decreased
Bone density decreased
Haematuria (presence of blood in urine)
Joint dislocation (a joint position is changed from normal position)
Neuropathy peripheral (surface nerve damage)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Pain

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Pain
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Skeletal injury (bone and supporting muscle injury)
Urticaria (rash of round, red welts on the skin that itch intensely)
Anxiety
Blood creatine increased
Depression
Emotional distress

60+:

Drug administration error

What are the existing conditions these people have? *

High Blood Cholesterol: 2 people, 11.76%
Depression: 2 people, 11.76%
Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 2 people, 11.76%
Stress And Anxiety: 1 person, 5.88%
Sleep Disorder: 1 person, 5.88%
Pain: 1 person, 5.88%
Ill-Defined Disorder: 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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