Lialda and Diclofenac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lialda (mesalamine) and Diclofenac (diclofenac). Common drug interactions include procedural pain among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Lialda and Diclofenac. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.

What is Diclofenac?

Diclofenac has active ingredients of diclofenac. eHealthMe is studying from 41,319 Diclofenac users. Check the latest studies of Diclofenac.

On Jul, 14, 2026

11 people who take Lialda and Diclofenac together, and have interactions are studied.

Lialda and Diclofenac drug interactions.

What are the common drug interactions of Lialda and Diclofenac, by gender? *:

female:

Procedural pain
Chronic kidney disease
Drug ineffective
Gastric cancer (stomach cancer)
Gastrointestinal necrosis (destruction of gastrointestinal organ)
Migraine (headache)
Renal injury (kidney injury)
Retinal depigmentation (change in colour of retina)
Septic shock (shock due to blood infection)

male:

Agitation (state of anxiety or nervous excitement)
Back pain
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Myocarditis (inflammation of heart muscle myocardium)
Palpitations (feelings or sensations that your heart is pounding or racing)
Parasomnia (sleep disorders that involve abnormal and unnatural movements, behaviours, emotions, perceptions)
Procedural complication
Rash
Restlessness (not able to rest)
Skin irritation

What are the common drug interactions of Lialda and Diclofenac, by age (0-1 to 60+)? *:

0-1:

Chest pain
Dizziness
Dyspnoea (difficult or laboured respiration)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Myocarditis (inflammation of heart muscle myocardium)
Cardiac arrest
Chest discomfort

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Agitation (state of anxiety or nervous excitement)
Hepatic enzyme increased
Iron deficiency anaemia
Palpitations (feelings or sensations that your heart is pounding or racing)
Parasomnia (sleep disorders that involve abnormal and unnatural movements, behaviours, emotions, perceptions)
Restlessness (not able to rest)

40-49:

n/a

50-59:

Retinal depigmentation (change in colour of retina)

60+:

Procedural pain

What are the existing conditions these people have? *

Infection: 4 people, 36.36%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 36.36%
Pain: 4 people, 36.36%
Oedema (fluid collection in tissue): 3 people, 27.27%
Blood Pressure Abnormal: 3 people, 27.27%
Cardiac Failure: 3 people, 27.27%
High Blood Cholesterol: 3 people, 27.27%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 27.27%
High Blood Pressure: 1 person, 9.09%
Gastric Disorder (disease of stomach): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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