Lialda and Enbrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lialda (mesalamine) and Enbrel (etanercept). Common drug interactions include pneumonia among females and basal cell carcinoma among males.

The phase IV clinical study analyzes what interactions people have when they take Lialda and Enbrel. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.

On Aug, 13, 2026

80 people who take Lialda and Enbrel together, and have interactions are studied.

What are the common drug interactions of Lialda and Enbrel, by gender? *:

female:

Pneumonia
Rectal cancer (cancer of rectum)
Thyroid neoplasm (tumour of thyroid)
Ulcer
Activities of daily living impaired
Adverse drug reaction
Dehydration (dryness resulting from the removal of water)
Feeling cold
Fistula (an abnormal connection or passageway between two)
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins)

male:

Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Drug effect decreased
Arthropathy
Asthma
Depressed mood
Injection site pruritus (severe itching at injection site)
Injection site swelling
Lung infection
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Rhinorrhoea (watery mucus discharge from the nose)

What are the common drug interactions of Lialda and Enbrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Injection site bruising
Oral infection

20-29:

n/a

30-39:

Depressed mood
Injection site bruising
Injection site pain
Injection site pruritus (severe itching at injection site)
Injection site swelling

40-49:

Drug ineffective
Pain
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Stress

50-59:

Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Prostatitis (inflammation of the prostate gland)
Rhinorrhoea (watery mucus discharge from the nose)
Skin cancer
Activities of daily living impaired
Dehydration (dryness resulting from the removal of water)
Drug effect decreased
Feeling cold
Fistula (an abnormal connection or passageway between two)
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins)

60+:

Arthralgia (joint pain)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphoria (generalized dissatisfaction with life)
Ear pain
Fatigue (feeling of tiredness)
Gait disturbance
Haemorrhagic diathesis (bleeding tendency)

What are the existing conditions these people have? *

Dizziness: 36 people, 45.00%
Pain: 16 people, 20.00%
Psoriasis (immune-mediated disease that affects the skin): 11 people, 13.75%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 10.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lialda and Enbrel?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously