Lialda and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lialda (mesalamine) and Keppra (levetiracetam). Common drug interactions include pulmonary oedema among females and upper gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Lialda and Keppra. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

On Jul, 10, 2026

13 people who take Lialda and Keppra together, and have interactions are studied.

What are the common drug interactions of Lialda and Keppra, by gender? *:

female:

Pulmonary oedema (fluid accumulation in the lungs)
Staphylococcal infection (an infection with staphylococcus bacteria)
Weight decreased
Fatigue (feeling of tiredness)
Pneumonia
Blood oestrogen decreased
Body temperature decreased
Diarrhoea
Dizziness
Drug effect decreased

male:

Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Back pain
Oropharyngeal pain
Pyrexia (fever)
Sepsis syndrome (a clinical condition of blood infection)
Synovitis (inflammation of the synovial membrane)
Cardiac valve disease (heart valve disease)
Cough
Diarrhoea
Drug ineffective

What are the common drug interactions of Lialda and Keppra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diarrhoea
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Oral pain
Stomatitis (inflammation of mucous membrane of mouth)

30-39:

n/a

40-49:

Back pain
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Neck pain
Occipital neuralgia (a condition characterized by chronic pain in the upper neck)

50-59:

Intervertebral disc protrusion (spinal disc protrusion)
Vertebral foraminal stenosis (narrowing of the intervertebral foramen)

60+:

Pulmonary oedema (fluid accumulation in the lungs)
Staphylococcal infection (an infection with staphylococcus bacteria)
Sepsis (a severe blood infection that can lead to organ failure and death)
Sepsis syndrome (a clinical condition of blood infection)
Synovitis (inflammation of the synovial membrane)
Weight decreased
Pneumonia
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Cardiac valve disease (heart valve disease)
Cough

What are the existing conditions these people have? *

Bone Marrow Conditioning Regimen: 3 people, 23.08%
Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 23.08%
Pain: 2 people, 15.38%
Muscle Spasms (muscle contraction): 2 people, 15.38%
Cardiac Disorder: 2 people, 15.38%
Stress And Anxiety: 1 person, 7.69%
Depression: 1 person, 7.69%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.69%
Brain Neoplasm Benign (non-cancerous tumour of brain): 1 person, 7.69%
Colitis (inflammation of colon): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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