Lialda and Pravachol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lialda (mesalamine) and Pravachol (pravastatin sodium). Common drug interactions include arthritis among females and device failure among males.

The phase IV clinical study analyzes what interactions people have when they take Lialda and Pravachol. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.

What is Pravachol?

Pravachol has active ingredients of pravastatin sodium. It is often used in high blood cholesterol. eHealthMe is studying from 24,382 Pravachol users. Check the latest studies of Pravachol.



On Jul, 17, 2026

22 people who take Lialda and Pravachol together, and have interactions are studied.

Lialda and Pravachol drug interactions.

What are the common drug interactions of Lialda and Pravachol, by gender? *:

female:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Cellulitis (infection under the skin)
  3. Fatigue (feeling of tiredness)
  4. Fibromyalgia (a long-term condition which causes pain all over the body)
  5. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  6. Injury
  7. Muscle rupture (tear in muscle)
  8. Peripheral swelling
  9. Skin warm
  10. Weight decreased

male:

  1. Device failure
  2. Diarrhoea
  3. Headache (pain in head)
  4. Pneumonia
  5. Vomiting

What are the common drug interactions of Lialda and Pravachol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Bone pain
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Diarrhoea
  4. Fatigue (feeling of tiredness)
  5. Glaucoma (increased fluid pressure in the eye with vision loss)
  6. Oedema peripheral (superficial swelling)
  7. Pain in extremity
  8. Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)

30-39:

n/a

40-49:

  1. Chest discomfort
  2. Discomfort
  3. Palpitations (feelings or sensations that your heart is pounding or racing)
  4. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

50-59:

  1. Breast cancer
  2. Depression
  3. Inflammatory bowel disease
  4. Injury
  5. Mean platelet volume decreased (less than normal average size of platelet cells in blood)
  6. Oedema peripheral (superficial swelling)
  7. Platelet count decreased
  8. Polyarthritis (arthritis which involves 5 or more joints simultaneously)
  9. White blood cell count decreased

60+:

  1. Injection site pain
  2. Arthralgia (joint pain)
  3. Fibromyalgia (a long-term condition which causes pain all over the body)
  4. Hypertension (high blood pressure)
  5. Injury
  6. Pain
  7. Peripheral vascular disorder
  8. Weight decreased
  9. Arrhythmia (irregular heartbeat)
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 22.73%
  2. High Blood Pressure: 4 people, 18.18%
  3. Asthma: 4 people, 18.18%
  4. Stress And Anxiety: 3 people, 13.64%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 13.64%
  6. Itching: 3 people, 13.64%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.64%
  8. Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 13.64%
  9. Depression: 3 people, 13.64%
  10. Cough: 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Lialda and Pravachol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lialda and Pravachol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lialda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pravachol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lialda and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pravachol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and pravastatin sodium (the active ingredients of Lialda and Pravachol, respectively), and Lialda and Pravachol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: