Lialda and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lialda (mesalamine) and Reglan (metoclopramide hydrochloride). Common drug interactions include amnesia among females and mental status changes among males.

The phase IV clinical study analyzes what interactions people have when they take Lialda and Reglan. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

On Jul, 16, 2026

23 people who take Lialda and Reglan together, and have interactions are studied.

What are the common drug interactions of Lialda and Reglan, by gender? *:

female:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ataxia (loss of full control of bodily movements)
Balance disorder
Cataract (clouding of the lens inside the eye)
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Dysarthria (speech disorder)
Gait disturbance
Hospitalisation
Injection site bruising

male:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Anaemia (lack of blood)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Pain
Pleural effusion (water on the lungs)
Pruritus generalised (generalized itching)
Somnolence (a state of near-sleep, a strong desire for sleep)
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Lialda and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Anxiety
Cholecystitis chronic (long lasting infection of gallbladder)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
General physical health deterioration (weak health status)
Injury
Pain
Pelvic venous thrombosis (blood clot occurring inside a blood vessel and thromboses (dvts) that form in the deep veins of the legs or in the pelvic veins)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)

20-29:

Hidradenitis (chronic disease of a type of sweat gland)
Nerve injury
Postoperative wound infection
Pulmonary embolism (blockage of the main artery of the lung)

30-39:

Injection site bruising
Diarrhoea
Fatigue (feeling of tiredness)
Injection site erythema (redness at injection site)
Injection site papule (solid pimple or swelling at injection site)
Injection site pruritus (severe itching at injection site)
Malaise (a feeling of general discomfort or uneasiness)

40-49:

Alopecia (absence of hair from areas of the body)
Hair colour changes
Hair disorder

50-59:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ataxia (loss of full control of bodily movements)
Balance disorder
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Dysarthria (speech disorder)
Gait disturbance
Muscular weakness (muscle weakness)
Neuropathy peripheral (surface nerve damage)
Spasmodic dysphonia (a voice disorder characterized by involuntary movements or spasms of one or more muscles of the larynx)

60+:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Anaemia (lack of blood)
Diarrhoea
Fatigue (feeling of tiredness)
Gingival bleeding (bleeding gums)
Hospitalisation
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Injection site bruising
Injection site erythema (redness at injection site)
Injection site pruritus (severe itching at injection site)

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 21.74%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 21.74%
Nausea (feeling of having an urge to vomit): 5 people, 21.74%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 17.39%
Inflammatory Bowel Disease: 4 people, 17.39%
Thyroid Diseases: 3 people, 13.04%
Colitis (inflammation of colon): 3 people, 13.04%
Dry Eyes (lack of adequate tears): 3 people, 13.04%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 13.04%
Headache (pain in head): 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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