Librium and Cogentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Librium (chlordiazepoxide hydrochloride) and Cogentin (benztropine mesylate). Common drug interactions include pancreatitis among females and neuroleptic malignant syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Librium and Cogentin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

On Aug, 01, 2026

14 people who take Librium and Cogentin together, and have interactions are studied.

What are the common drug interactions of Librium and Cogentin, by gender? *:

female:

Pancreatitis (inflammation of pancreas)
Pharyngolaryngeal pain
Respiratory tract congestion (blockage on respiratory system)
Abdominal pain
Abnormal behaviour
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Apnoea (suspension of external breathing)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Confusional state
Costochondritis (chest wall pain)

male:

Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Attention deficit/hyperactivity disorder
Panic attack
Parkinson's disease
Post-traumatic stress disorder
Pruritus (severe itching of the skin)
Pyrexia (fever)
Restless legs syndrome (a powerful urge to move your legs)
Type 2 diabetes mellitus
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Librium and Cogentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Pyrexia (fever)
Type 2 diabetes mellitus
Acute hepatic failure
Anaemia macrocytic (a macrocytic class of anaemia)
Blood creatine phosphokinase increased
Chills (felling of cold)
Crepitations (noises are produced by the rubbing of parts one against the other)
Delirium (wild excitement)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)

30-39:

Postnasal drip
Productive cough
Pupils unequal
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Respiratory depression (respiration has a rate below 12 breaths)
Respiratory distress (difficulty in breathing)
Sensation of pressure in ear
Tongue disorder (disease of tongue)
Ulcer
Vomiting

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Dyslipidaemia (abnormal amount of lipids)
Hyperglycaemia (high blood sugar)
Hyperlipidaemia (presence of excess lipids in the blood)
Impaired gastric emptying
Neuropathy peripheral (surface nerve damage)
Obesity (having too much body fat)
Pancreatitis acute (sudden inflammation of pancreas)

50-59:

n/a

60+:

Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)

What are the existing conditions these people have? *

Pain: 8 people, 57.14%
Depression: 5 people, 35.71%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 28.57%
Bipolar Disorder (mood disorder): 3 people, 21.43%
Agitation (state of anxiety or nervous excitement): 2 people, 14.29%
Parkinson's Disease: 2 people, 14.29%
Thinking Abnormal: 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%
Alcohol Withdrawal Syndrome: 1 person, 7.14%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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