Librium and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Librium (chlordiazepoxide hydrochloride) and Reglan (metoclopramide hydrochloride). Common drug interactions include diarrhoea among females and weakness among males.

The phase IV clinical study analyzes what interactions people have when they take Librium and Reglan. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

On Aug, 09, 2026

33 people who take Librium and Reglan together, and have interactions are studied.

What are the common drug interactions of Librium and Reglan, by gender? *:

female:

Diarrhoea
Dizziness
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)
Hepatic steatosis (fatty liver disease)
Hepatomegaly (abnormal enlargement of the liver)
Insomnia (sleeplessness)
Loss of consciousness
Muscle twitching

male:

Weakness
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dysarthria (speech disorder)
Electrolyte imbalance
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Oliguria (not enough urine)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Wheezing (a high-pitched whistling sound made while you breath)

What are the common drug interactions of Librium and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Abnormal behaviour
Anaemia (lack of blood)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Catheter sepsis (bacterial infection in blood due to catheter)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)

30-39:

n/a

40-49:

Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)
Abdominal pain upper
Affect lability (emotional incontinence)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood cholesterol increased
Chest pain
Coagulopathy (blood's ability to clot is impaired)
Coma (state of unconsciousness lasting more than six hours)

50-59:

Abdominal distension
Abdominal pain
Abdominal pain upper
Agitation (state of anxiety or nervous excitement)
Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
Back pain
Balance disorder
Blood pressure increased
Bradycardia (abnormally slow heart action)
Chest pain

60+:

Fluid overload (too much fluid in the blood)
Renal failure (kidney dysfunction)
Actinic keratosis (skin disease due to sun exposure)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Apnoea (suspension of external breathing)
Arthralgia (joint pain)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 12.12%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.12%
Pain: 3 people, 9.09%
High Blood Cholesterol: 3 people, 9.09%
Diabetes: 3 people, 9.09%
Depression: 3 people, 9.09%
Neuropathy Peripheral (surface nerve damage): 2 people, 6.06%
Gout (uric acid crystals building up in the body): 2 people, 6.06%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 6.06%
Cardiac Disorder: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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