Lidocaine and Plendil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lidocaine (lidocaine) and Plendil (felodipine). Common drug interactions include arthralgia among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Lidocaine and Plendil. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lidocaine?

Lidocaine has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 27,555 Lidocaine users. Check the latest studies of Lidocaine.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

On Jul, 19, 2026

18 people who take Lidocaine and Plendil together, and have interactions are studied.

Lidocaine and Plendil drug interactions.

What are the common drug interactions of Lidocaine and Plendil, by gender? *:

female:

Arthralgia (joint pain)
Atrophy (wasting away of a part of the body)
Dry skin
Exfoliative rash (scaly red generalized skin rash)
Gait disturbance
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)

male:

Renal failure (kidney dysfunction)
Coagulation factor deficiency (lack of clotting substance in blood)
Acute stress disorder
Blood alkaline phosphatase increased
Gamma-glutamyltransferase increased
Nausea (feeling of having an urge to vomit)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Fear

What are the common drug interactions of Lidocaine and Plendil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Generalised oedema (swelling all over the body)
Stress
Finger deformity (a deformed position of the finger)
Muscular weakness (muscle weakness)
Skin induration (an abnormally hard spot or area on the skin)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Drug toxicity
Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
Hand deformity
Muscle contracture (a permanent shortening of a muscle)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Death
Emotional distress
Fear
Injury
Multi-organ failure (multisystem organ failure)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)

50-59:

Coagulation factor deficiency (lack of clotting substance in blood)
Haemorrhage (bleeding)
Heparin-induced thrombocytopenia
Pyrexia (fever)
Renal failure (kidney dysfunction)
Decreased appetite
Diarrhoea
Hypotension (abnormally low blood pressure)
Acute stress disorder
Blood alkaline phosphatase increased

60+:

Injury
Pneumonia
Fear
Glycosylated haemoglobin increased
Haematocrit decreased
Multi-organ failure (multisystem organ failure)
Renal failure acute (rapid kidney dysfunction)
Renal impairment (severely reduced kidney function)
Stress
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 6 people, 33.33%
Nuclear Magnetic Resonance Imaging Brain: 5 people, 27.78%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 4 people, 22.22%
Neuralgia (pain in one or more nerves): 4 people, 22.22%
Nausea And Vomiting: 4 people, 22.22%
Anaesthesia: 4 people, 22.22%
Indigestion: 4 people, 22.22%
Bradycardia (abnormally slow heart action): 4 people, 22.22%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 22.22%
Headache (pain in head): 4 people, 22.22%

* Approximation only. Some reports may have incomplete information.

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