Lidoderm and Cabometyx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lidoderm (lidocaine) and Cabometyx (cabozantinib s-malate). Common drug interactions include death among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Lidoderm and Cabometyx. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.

What is Cabometyx?

Cabometyx has active ingredients of cabozantinib s-malate. eHealthMe is studying from 35,069 Cabometyx users. Check the latest studies of Cabometyx.



On Jul, 21, 2026

24 people who take Lidoderm and Cabometyx together, and have interactions are studied.

Lidoderm and Cabometyx drug interactions.

What are the common drug interactions of Lidoderm and Cabometyx, by gender? *:

female:

  1. Death
  2. Asthenia (weakness)
  3. Blood pressure decreased
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Dizziness
  6. Electrolyte depletion (act of decreasing electrolyte markedly)
  7. Gastrointestinal motility disorder (abnormal intestinal contractions)
  8. Haematemesis (vomiting of blood)
  9. Hypervolaemia (abnormally increased volume of blood)
  10. Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Decreased appetite
  3. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  4. Dyspnoea (difficult or laboured respiration)
  5. Mucosal inflammation (infection of mucous membrane)
  6. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  7. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  8. Pneumonia bacterial (pneumonia associated with bacterial infection)
  9. Pulmonary embolism (blockage of the main artery of the lung)
  10. Pulmonary mass

What are the common drug interactions of Lidoderm and Cabometyx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Platelet count decreased

50-59:

  1. Thrombosis (formation of a blood clot inside a blood vessel)
  2. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  3. Nausea (feeling of having an urge to vomit)
  4. Pneumonia bacterial (pneumonia associated with bacterial infection)
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Pulmonary mass
  7. Renal mass (mass in kidney)
  8. Vomiting
  9. Decreased appetite
  10. Depression

60+:

  1. Death
  2. Asthenia (weakness)
  3. Metastases to kidney (cancer spreads to kidney)
  4. Metastases to liver (cancer spreads to liver)
  5. Metastases to muscle (cancer spreads to muscle)
  6. Nausea (feeling of having an urge to vomit)
  7. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  8. Oedema peripheral (superficial swelling)
  9. Pallor
  10. Pericardial effusion (fluid around the heart)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 21 people, 87.50%

* Approximation only. Some reports may have incomplete information.

Do you take Lidoderm and Cabometyx?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lidoderm and Cabometyx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lidoderm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cabometyx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lidoderm and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cabometyx and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lidocaine and cabozantinib s-malate (the active ingredients of Lidoderm and Cabometyx, respectively), and Lidoderm and Cabometyx (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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