Lidoderm and Oxybutynin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lidoderm (lidocaine) and Oxybutynin (oxybutynin). Common drug interactions include productive cough among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Lidoderm and Oxybutynin. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.

What is Oxybutynin?

Oxybutynin has active ingredients of oxybutynin. It is often used in urge incontinence. eHealthMe is studying from 23,143 Oxybutynin users. Check the latest studies of Oxybutynin.

On Jul, 16, 2026

93 people who take Lidoderm and Oxybutynin together, and have interactions are studied.

Lidoderm and Oxybutynin drug interactions.

What are the common drug interactions of Lidoderm and Oxybutynin, by gender? *:

female:

Productive cough
Skin ulcer
Small intestinal obstruction (blockage in small intestine)
Spinal stenosis (narrowing of spinal column)
Surgery
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Urinary tract infection
Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Anxiety

male:

Asthenia (weakness)
Death
Influenza
Liver injury
Melaena (the passage of black, tarry stools)
Neutropenia (an abnormally low number of neutrophils)
Suicide attempt
Urinary retention (the inability to completely or partially empty the bladder)
Urinary tract infection
Renal failure (kidney dysfunction)

What are the common drug interactions of Lidoderm and Oxybutynin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal hernia
Influenza like illness
Injection site erythema (redness at injection site)
Injection site swelling
Nausea (feeling of having an urge to vomit)
Small intestinal obstruction (blockage in small intestine)

20-29:

n/a

30-39:

Altered state of consciousness (altered state of mind)
Fatigue (feeling of tiredness)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Post-traumatic stress disorder
Weight decreased

40-49:

Gastric bypass
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Urinary tract infection
Blood glucose increased
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

50-59:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cold sweat
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Depressed level of consciousness
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Emotional distress

60+:

Urinary tract infection
Diarrhoea
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nasopharyngitis (inflammation of the nasopharynx)
Nephrogenic anaemia (anaemia due to kidney disease)
Sinusitis (inflammation of sinus)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Urinary tract infection enterococcal
Viral infection

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 23 people, 24.73%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 20 people, 21.51%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 18 people, 19.35%
High Blood Cholesterol: 15 people, 16.13%
Hypersensitivity: 13 people, 13.98%
Constipation: 13 people, 13.98%
High Blood Pressure: 13 people, 13.98%
Stress And Anxiety: 12 people, 12.90%
Depression: 11 people, 11.83%
Nausea (feeling of having an urge to vomit): 9 people, 9.68%

* Approximation only. Some reports may have incomplete information.

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