Linaclotide and Apixaban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Linaclotide (linaclotide) and Apixaban (apixaban). Common drug interactions include cough among females and deep vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Linaclotide and Apixaban. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Linaclotide?

Linaclotide has active ingredients of linaclotide. eHealthMe is studying from 2,197 Linaclotide users. Check the latest studies of Linaclotide.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.

On Jul, 12, 2026

14 people who take Linaclotide and Apixaban together, and have interactions are studied.

Linaclotide and Apixaban drug interactions.

What are the common drug interactions of Linaclotide and Apixaban, by gender? *:

female:

Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Eye disorder
Fall
Flushing (the warm, red condition of human skin)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatic steatosis (fatty liver disease)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypertension (high blood pressure)

male:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Haemorrhage intracranial (bleeding within the skull)
Intraventricular haemorrhage (intraventricular bleeding)

What are the common drug interactions of Linaclotide and Apixaban, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Asthma
Chronic kidney disease
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatic steatosis (fatty liver disease)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypertension (high blood pressure)
Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body)
Myalgia (muscle pain)

60+:

Abdominal pain
Large intestine perforation (hole in large intestine)
Intraventricular haemorrhage (intraventricular bleeding)
Pain
Tremor (trembling or shaking movements in one or more parts of your body)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Coagulation time shortened
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fall

What are the existing conditions these people have? *

Endometrial Cancer: 3 people, 21.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 14.29%
Pneumonia Bacterial (pneumonia associated with bacterial infection): 2 people, 14.29%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.14%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 1 person, 7.14%
Breast Cancer Female: 1 person, 7.14%
Cardiac Failure Chronic: 1 person, 7.14%
Cardiac Failure Congestive: 1 person, 7.14%
Constipation: 1 person, 7.14%
Dizziness: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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