Linaclotide and Ezetimibe drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Linaclotide (linaclotide) and Ezetimibe (ezetimibe). Common drug interactions include abdominal distension among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Linaclotide and Ezetimibe. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Linaclotide?

Linaclotide has active ingredients of linaclotide. eHealthMe is studying from 2,197 Linaclotide users. Check the latest studies of Linaclotide.

What is Ezetimibe?

Ezetimibe has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 30,849 Ezetimibe users. Check the latest studies of Ezetimibe.

On Jul, 20, 2026

17 people who take Linaclotide and Ezetimibe together, and have interactions are studied.

Linaclotide and Ezetimibe drug interactions.

What are the common drug interactions of Linaclotide and Ezetimibe, by gender? *:

female:

Abdominal distension
Lip swelling
Rash pruritic (redness with itching)
Swelling face
Abdominal pain
Abdominal pain upper
Adverse drug reaction
Asthenia (weakness)
Chest pain
Chronic kidney disease

male:

Diarrhoea
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Oral administration complication
Osteopenia (a condition where bone mineral density is lower than normal)
Vitamin d deficiency
Vomiting

What are the common drug interactions of Linaclotide and Ezetimibe, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Urticaria (rash of round, red welts on the skin that itch intensely)
Lip swelling
Rash pruritic (redness with itching)
Swelling face

50-59:

Abdominal pain
Chest pain
Diarrhoea
Dizziness
Hyperhidrosis (abnormally increased sweating)
Malaise (a feeling of general discomfort or uneasiness)

60+:

Abdominal distension
Abdominal pain upper
Food aversion (we reject certain foods for a reason)
Headache (pain in head)
Klebsiella infection
Nausea (feeling of having an urge to vomit)
Oligodipsia (abnormal absence of thirst)
Oral administration complication
Ulcer
Urinary tract infection bacterial

What are the existing conditions these people have? *

Constipation: 7 people, 41.18%
Pain: 4 people, 23.53%
Asthma: 2 people, 11.76%
Infection: 2 people, 11.76%
Nausea (feeling of having an urge to vomit): 2 people, 11.76%
Stress And Anxiety: 2 people, 11.76%
Cardiac Disorder: 1 person, 5.88%
Chest Pain: 1 person, 5.88%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 5.88%
Breakthrough Pain: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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