Linagliptin and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Linagliptin (linagliptin) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include genital ulceration among females and neurotoxicity among males.

The phase IV clinical study analyzes what interactions people have when they take Linagliptin and Valacyclovir. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Linagliptin?

Linagliptin has active ingredients of linagliptin. eHealthMe is studying from 8,112 Linagliptin users. Check the latest studies of Linagliptin.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On Jul, 21, 2026

61 people who take Linagliptin and Valacyclovir together, and have interactions are studied.

Linagliptin and Valacyclovir drug interactions.

What are the common drug interactions of Linagliptin and Valacyclovir, by gender? *:

female:

Genital ulceration (ulcers on sex organ)
Dizziness
Fatigue (feeling of tiredness)
Osteomyelitis (infection of bone)
Pyrexia (fever)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Bile duct stone
Blood pressure increased
Blood pressure systolic increased
Burning sensation

male:

Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Confusional state
Diarrhoea
General physical health deterioration (weak health status)
Blood creatinine increased
Constipation
Device related infection
Folliculitis (infection of hair root)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

What are the common drug interactions of Linagliptin and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pneumonia
Pyrexia (fever)
Respiratory tract infection

50-59:

Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Confusional state
Aphasia (damage to the parts of the brain that control language)
Agitation (state of anxiety or nervous excitement)
Asterixis (flapping tremor, or liver flap)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Overdose
Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)
Rash erythematous (redness of the skin)

60+:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
White blood cell count decreased
Genital ulceration (ulcers on sex organ)
Febrile neutropenia (fever with reduced white blood cells)
Death
Dizziness
Oral herpes (viral infection of mouth)
Osteomyelitis (infection of bone)
Pneumonia

What are the existing conditions these people have? *

Herpes Zoster: 19 people, 31.15%
High Blood Pressure: 18 people, 29.51%
Diabetes: 18 people, 29.51%
Multiple Myeloma (cancer of the plasma cells): 14 people, 22.95%
Depression: 12 people, 19.67%
Gout (uric acid crystals building up in the body): 11 people, 18.03%
Hyperlipidaemia (presence of excess lipids in the blood): 8 people, 13.11%
Viral Infection: 7 people, 11.48%
Type 2 Diabetes: 7 people, 11.48%
Rash Erythematous (redness of the skin): 7 people, 11.48%

* Approximation only. Some reports may have incomplete information.

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