Lioresal and Movicol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lioresal (baclofen) and Movicol (polyethylene glycol 3350). Common drug interactions include alopecia among females and dyskinesia among males.

The phase IV clinical study analyzes what interactions people have when they take Lioresal and Movicol. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Lioresal?

Lioresal has active ingredients of baclofen. It is often used in multiple sclerosis. eHealthMe is studying from 20,572 Lioresal users. Check the latest studies of Lioresal.

What is Movicol?

Movicol has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 14,249 Movicol users. Check the latest studies of Movicol.

On Jul, 08, 2026

43 people who take Lioresal and Movicol together, and have interactions are studied.

What are the common drug interactions of Lioresal and Movicol, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Aphthous ulcer (mouth ulcer)
Aspartate aminotransferase increased
Asthenia (weakness)
Blood alkaline phosphatase increased
Blood pressure fluctuation
Drug effect decreased
Femur fracture
Gamma-glutamyltransferase increased
Hemiparesis (weakness on one side of the body)

male:

Dyskinesia (abnormality or impairment of voluntary movement)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug ineffective
Altered state of consciousness (altered state of mind)
Confusional state
Encephalopathy (functioning of the brain is affected by some agent or condition)
Femur fracture
Hyperkinesia (higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs)

What are the common drug interactions of Lioresal and Movicol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Bradycardia (abnormally slow heart action)
Femur fracture
Alopecia (absence of hair from areas of the body)
Cardiac failure
Death
Decreased appetite
Fatigue (feeling of tiredness)
Pneumonia
Weight decreased
Wheezing (a high-pitched whistling sound made while you breath)

20-29:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Pyrexia (fever)

30-39:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Varicella

40-49:

Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Fatigue (feeling of tiredness)
Headache (pain in head)
Abdominal pain
Anorectal disorder
Balance disorder
Burning sensation
Chest discomfort

50-59:

Nervous system disorder (a general class of medical conditions affecting the nervous system)
Disease progression
Aphthous ulcer (mouth ulcer)
Death
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Fatigue (feeling of tiredness)
Femur fracture
Leukopenia (less number of white blood cells in blood)
Neoplasm progression (growth of tumour)
Pelvic fracture

60+:

Dyskinesia (abnormality or impairment of voluntary movement)
Urinary tract infection
Weight decreased
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Coma (state of unconsciousness lasting more than six hours)
Drug ineffective
Altered state of consciousness (altered state of mind)
Confusional state
Cystitis (inflammation of the wall of the bladder)
Encephalopathy (functioning of the brain is affected by some agent or condition)

What are the existing conditions these people have? *

Parkinson's Disease: 7 people, 16.28%
Hypertransaminasaemia: 6 people, 13.95%
Muscle Spasms (muscle contraction): 5 people, 11.63%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 9.30%
Pain: 4 people, 9.30%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 4 people, 9.30%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 6.98%
Osteoporosis (bones weak and more likely to break): 3 people, 6.98%
Dysmenorrhea (painful menstruation): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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