Lipitor and Opana er drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lipitor (atorvastatin calcium) and Opana er (oxymorphone hydrochloride). Common drug interactions include renal failure among females and drug effect decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Lipitor and Opana er. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,048 Lipitor users. Check the latest studies of Lipitor.

What is Opana er?

Opana er has active ingredients of oxymorphone hydrochloride. It is often used in pain. eHealthMe is studying from 33,986 Opana er users. Check the latest studies of Opana er.



On Jul, 31, 2026

38 people who take Lipitor and Opana er together, and have interactions are studied.

Lipitor and Opana er drug interactions.

What are the common drug interactions of Lipitor and Opana Er, by gender? *:

female:

  1. Renal failure (kidney dysfunction)
  2. Renal failure chronic (long lasting kidney dysfunction)
  3. Rib fracture
  4. Seasonal allergy (allergic condition due to certain season)
  5. Skin haemorrhage (bleeding into skin)
  6. Somatoform disorder (a mental disorder characterized by symptoms that suggest physical illness or injury)
  7. Spinal disorder (disease of spine a back bone)
  8. Spinal fusion surgery
  9. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  10. Swollen tongue (swelling of tongue)

male:

  1. Drug effect decreased
  2. Headache (pain in head)
  3. Drug screen positive
  4. Ear pain
  5. Fatigue (feeling of tiredness)
  6. Feeding disorder (when children refuse to eat certain food groups)
  7. Gait disturbance
  8. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  9. Impaired driving ability
  10. Infection

What are the common drug interactions of Lipitor and Opana Er, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Fatigue (feeling of tiredness)
  2. Chest pain
  3. Constipation
  4. Dizziness
  5. Influenza like illness
  6. Nausea (feeling of having an urge to vomit)
  7. Oxygen saturation decreased
  8. Vomiting
  9. Dysphagia (a condition in which swallowing is difficult or painful)
  10. Hypotension (abnormally low blood pressure)

50-59:

  1. Affective disorder (mental disorder)
  2. Fibromyalgia (a long-term condition which causes pain all over the body)
  3. General physical condition
  4. Sleep disorder
  5. Nausea (feeling of having an urge to vomit)
  6. Aggression
  7. Anxiety
  8. Asthenia (weakness)
  9. Castleman's disease (a disease of lymph nodes and related tissues)
  10. Chest pain

60+:

  1. Fall
  2. Chronic kidney disease
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Arthropathy
  5. Cardiac disorder
  6. Confusional state
  7. Constipation
  8. Cystitis (inflammation of the wall of the bladder)
  9. Death
  10. Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 31.58%
  2. Back Pain: 11 people, 28.95%
  3. Depression: 9 people, 23.68%
  4. High Blood Pressure: 9 people, 23.68%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 18.42%
  6. Oedema (fluid collection in tissue): 5 people, 13.16%
  7. Wound: 5 people, 13.16%
  8. Infection: 5 people, 13.16%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 10.53%
  10. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lipitor and Opana er:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lipitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Opana er:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lipitor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Opana er and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on atorvastatin calcium and oxymorphone hydrochloride (the active ingredients of Lipitor and Opana er, respectively), and Lipitor and Opana er (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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