Lipitor and Pepcid rpd drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lipitor (atorvastatin calcium) and Pepcid rpd (famotidine). Common drug interactions include aplastic anaemia among females and liver disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Lipitor and Pepcid rpd. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,050 Lipitor users. Check the latest studies of Lipitor.

What is Pepcid rpd?

Pepcid rpd has active ingredients of famotidine. eHealthMe is studying from 1,197 Pepcid rpd users. Check the latest studies of Pepcid rpd.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

80 people who take Lipitor and Pepcid rpd together, and have interactions are studied.

Lipitor and Pepcid rpd drug interactions.

What are the common drug interactions of Lipitor and Pepcid Rpd, by gender? *:

female:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Ascites (accumulation of fluid in the abdominal cavity)
Aspartate aminotransferase increased
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood creatine phosphokinase increased
Blood immunoglobulin e increased
Chills (felling of cold)
Collagen disorder (infection and weakness of collagen)
Eosinophil count increased
Eosinophilia (eosinophil count in the peripheral blood exceeds)

male:

Liver disorder (liver diseases)
Blood creatine phosphokinase increased
Myopathy (a muscular disease in which the muscle fibres do not function)
Blood alkaline phosphatase increased
Blood bilirubin increased
Colonic polyp (extra part of colon tissue grow in intestine)
Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)
Hepatocellular damage (liver damage)
Muscle enzyme increased
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Lipitor and Pepcid Rpd, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

40-49:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood creatine phosphokinase increased
Gamma-glutamyltransferase increased
Liver disorder (liver diseases)
Lymphocyte stimulation test positive
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Myoglobin blood increased (presence of myoglobin in blood increased)
Myoglobin urine present

50-59:

Vomiting
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)
Biliary dilatation
Constipation
Gallbladder disorder
Hepatic trauma (liver injury)
Hepatitis acute
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Lymphocyte stimulation test positive

60+:

Liver disorder (liver diseases)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Anaemia (lack of blood)
Aspartate aminotransferase increased
Colonic polyp (extra part of colon tissue grow in intestine)
Gamma-glutamyltransferase increased
Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)
Jaundice cholestatic
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

What are the existing conditions these people have? *

Hyperlipidaemia (presence of excess lipids in the blood): 33 people, 41.25%
High Blood Pressure: 17 people, 21.25%
Gastritis (inflammation of stomach): 12 people, 15.00%
Gastric Ulcer (stomach ulcer): 6 people, 7.50%
Diabetes: 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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