Lipitor and Rizatriptan benzoate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lipitor (atorvastatin calcium) and Rizatriptan benzoate (rizatriptan benzoate). Common drug interactions include atrial fibrillation among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Lipitor and Rizatriptan benzoate. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,048 Lipitor users. Check the latest studies of Lipitor.

What is Rizatriptan benzoate?

Rizatriptan benzoate has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 1,886 Rizatriptan benzoate users. Check the latest studies of Rizatriptan benzoate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 17, 2026

14 people who take Lipitor and Rizatriptan benzoate together, and have interactions are studied.

Lipitor and Rizatriptan benzoate drug interactions.

What are the common drug interactions of Lipitor and Rizatriptan Benzoate, by gender? *:

female:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Dizziness
  4. Abdominal discomfort
  5. Anxiety disorder
  6. Ataxia (loss of full control of bodily movements)
  7. Cardiac aneurysm (a condition that can occur after a myocardial infarction due to the inadequate resistance of the new scar tissue to the systolic pressure)
  8. Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
  9. Depression
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

male:

  1. Abdominal pain upper
  2. Arthralgia (joint pain)
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Skin disorder (skin disease)
  5. Decreased appetite
  6. Diarrhoea
  7. Nausea (feeling of having an urge to vomit)
  8. Pain in extremity
  9. Vomiting
  10. Gastric disorder (disease of stomach)

What are the common drug interactions of Lipitor and Rizatriptan Benzoate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Cardiac aneurysm (a condition that can occur after a myocardial infarction due to the inadequate resistance of the new scar tissue to the systolic pressure)

40-49:

n/a

50-59:

  1. Abdominal pain upper
  2. Arthralgia (joint pain)
  3. Decreased appetite
  4. Diarrhoea
  5. Nausea (feeling of having an urge to vomit)
  6. Pain in extremity
  7. Vomiting
  8. Gastric disorder (disease of stomach)
  9. Gout (uric acid crystals building up in the body)
  10. Ear haemorrhage (bleeding from ear)

60+:

  1. Dizziness
  2. Abdominal discomfort
  3. Loss of consciousness
  4. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  5. Muscle spasms (muscle contraction)
  6. Poor quality sleep
  7. Psychotic disorder
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  10. Visual impairment

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 35.71%
  2. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 21.43%
  3. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.14%
  4. High Blood Pressure: 1 person, 7.14%
  5. Affective Disorder (mental disorder): 1 person, 7.14%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.14%
  7. Bipolar Disorder (mood disorder): 1 person, 7.14%
  8. Cardiac Disorder: 1 person, 7.14%
  9. Depression: 1 person, 7.14%
  10. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lipitor and Rizatriptan benzoate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lipitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rizatriptan benzoate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lipitor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rizatriptan benzoate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on atorvastatin calcium and rizatriptan benzoate (the active ingredients of Lipitor and Rizatriptan benzoate, respectively), and Lipitor and Rizatriptan benzoate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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