Lipitor and Zelboraf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lipitor (atorvastatin calcium) and Zelboraf (vemurafenib). Common drug interactions include diarrhoea among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Lipitor and Zelboraf. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,048 Lipitor users. Check the latest studies of Lipitor.

What is Zelboraf?

Zelboraf has active ingredients of vemurafenib. eHealthMe is studying from 8,392 Zelboraf users. Check the latest studies of Zelboraf.

On Aug, 06, 2026

40 people who take Lipitor and Zelboraf together, and have interactions are studied.

What are the common drug interactions of Lipitor and Zelboraf, by gender? *:

female:

Diarrhoea
Dry skin
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Death
Arthropathy
Asthenia (weakness)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Breast tenderness
Cellulitis (infection under the skin)

male:

Rash
Sunburn
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Weight decreased
Cardiac disorder
Chest pain
Drug effect decreased
Lung infection
Nausea (feeling of having an urge to vomit)
Pneumonia

What are the common drug interactions of Lipitor and Zelboraf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Death
Depression
Diarrhoea
Drug effect decreased
Eye pruritus (eye itching)
Headache (pain in head)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hyperkeratosis (thickening of the outer layer of the skin)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Ocular hyperaemia (an abnormally large amount of blood in eye)

60+:

Rash
Arthralgia (joint pain)
Weight decreased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac disorder
Chest pain
Lung infection
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Keratoacanthoma (a common low-grade (unlikely to metastasize or invade) skin tumour that is believed to originate from the neck of the hair follicle)

What are the existing conditions these people have? *

Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 17 people, 42.50%
Malignant Melanoma (skin cancer rises from melancytes): 16 people, 40.00%
High Blood Pressure: 8 people, 20.00%
Pain: 5 people, 12.50%
Stress And Anxiety: 4 people, 10.00%
Diabetes: 4 people, 10.00%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 7.50%
Dyslipidaemia (abnormal amount of lipids): 3 people, 7.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.00%
Heart Rate Increased: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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