Lipoic acid and Pepcid ac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lipoic acid (alpha - lipoic acid) and Pepcid ac (famotidine). Common drug interactions include arthralgia among females.

The phase IV clinical study analyzes what interactions people have when they take Lipoic acid and Pepcid ac. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Lipoic acid?

Lipoic acid has active ingredients of alpha - lipoic acid. It is often used in peripheral neuropathy. eHealthMe is studying from 5,920 Lipoic acid users. Check the latest studies of Lipoic acid.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,573 Pepcid ac users. Check the latest studies of Pepcid ac.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 02, 2026

13 people who take Lipoic acid and Pepcid ac together, and have interactions are studied.

Lipoic acid and Pepcid ac drug interactions.

What are the common drug interactions of Lipoic Acid and Pepcid Ac, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Facial pain
  4. Fatigue (feeling of tiredness)
  5. Haemorrhage (bleeding)
  6. Headache (pain in head)
  7. Infusion related reaction
  8. Joint swelling
  9. Lymphadenopathy (disease or enlargement of lymph nodes)
  10. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

male:

n/a

What are the common drug interactions of Lipoic Acid and Pepcid Ac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  2. Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
  3. Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Nerve compression
  6. Nerve injury
  7. Neuralgia (pain in one or more nerves)
  8. Peripheral swelling
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Weight decreased

50-59:

  1. Visual impairment
  2. Abdominal discomfort
  3. Arthralgia (joint pain)
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Back disorder
  6. Bone pain
  7. Neck pain
  8. Pyrexia (fever)
  9. Thyroid mass

60+:

  1. Death
  2. Diarrhoea

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 23.08%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 23.08%
  3. Drowsiness: 3 people, 23.08%
  4. Immunodeficiency Common Variable: 3 people, 23.08%
  5. Indigestion: 2 people, 15.38%
  6. Hypersensitivity: 1 person, 7.69%
  7. High Blood Pressure: 1 person, 7.69%
  8. High Blood Cholesterol: 1 person, 7.69%
  9. Hair Loss: 1 person, 7.69%
  10. Haemoglobin Decreased: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Lipoic acid and Pepcid ac?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lipoic acid and Pepcid ac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lipoic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pepcid ac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lipoic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pepcid ac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on alpha - lipoic acid and famotidine (the active ingredients of Lipoic acid and Pepcid ac, respectively), and Lipoic acid and Pepcid ac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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