Lithium carbonate and Combivir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lithium carbonate (lithium carbonate) and Combivir (lamivudine; zidovudine). Common drug interactions include cushing's syndrome among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Lithium carbonate and Combivir. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Lithium carbonate?

Lithium carbonate has active ingredients of lithium carbonate. It is often used in bipolar disorder. eHealthMe is studying from 25,652 Lithium carbonate users. Check the latest studies of Lithium carbonate.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.



On Jul, 31, 2026

25 people who take Lithium carbonate and Combivir together, and have interactions are studied.

Lithium carbonate and Combivir drug interactions.

What are the common drug interactions of Lithium Carbonate and Combivir, by gender? *:

female:

  1. Cushing's syndrome (obesity, a rounded face, increased fat)
  2. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  3. Hepatic failure (liver failure)
  4. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
  5. Liver transplant
  6. Chorioamnionitis (inflammation of the fetal membranes (amnion and chorion) due to a bacterial infection)
  7. Cushingoid (obesity and weakening of the muscles)
  8. Dexamethasone suppression test positive
  9. Dysgeusia (disorder of the sense of taste)
  10. Dysphemia (stammering or stuttering)

male:

  1. Fatigue (feeling of tiredness)
  2. Pain
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Diabetic coma
  5. Diabetic complication
  6. Foot fracture
  7. Heart valve incompetence (heart's valves do not work correctly)
  8. Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
  9. Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia)
  10. Oesophageal carcinoma (cancer tumour of oesophagus)

What are the common drug interactions of Lithium Carbonate and Combivir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Chronic kidney disease
  5. Cushing's syndrome (obesity, a rounded face, increased fat)
  6. Decreased activity
  7. Depression
  8. Diarrhoea
  9. Emotional distress
  10. Fatigue (feeling of tiredness)

40-49:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Diabetic coma
  3. Diabetic complication
  4. Foot fracture
  5. Heart valve incompetence (heart's valves do not work correctly)
  6. Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
  7. Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia)
  8. Oesophageal carcinoma (cancer tumour of oesophagus)
  9. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  10. Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Ataxia (loss of full control of bodily movements)
  4. Bone density decreased
  5. Chronic kidney disease
  6. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  7. Diarrhoea
  8. Dysarthria (speech disorder)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Pain in extremity

60+:

n/a

What are the existing conditions these people have? *

  1. Hiv Infection: 11 people, 44.00%
  2. Stress And Anxiety: 4 people, 16.00%
  3. Oesophageal Carcinoma (cancer tumour of oesophagus): 3 people, 12.00%
  4. Depression: 3 people, 12.00%
  5. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 12.00%
  6. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 8.00%
  7. Lactose Intolerance (inability to digest lactose): 2 people, 8.00%
  8. Inflammation: 2 people, 8.00%
  9. Skin Disorder (skin disease): 2 people, 8.00%
  10. Pain: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lithium carbonate and Combivir?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lithium carbonate and Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lithium carbonate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lithium carbonate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lithium carbonate and lamivudine; zidovudine (the active ingredients of Lithium carbonate and Combivir, respectively), and Lithium carbonate and Combivir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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