Lodine and Lantus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lodine (etodolac) and Lantus (insulin glargine recombinant). Common drug interactions include rhinorrhoea among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Lodine and Lantus. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Lodine?

Lodine has active ingredients of etodolac. It is often used in pain. eHealthMe is studying from 3,846 Lodine users. Check the latest studies of Lodine.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.

On Jul, 16, 2026

24 people who take Lodine and Lantus together, and have interactions are studied.

What are the common drug interactions of Lodine and Lantus, by gender? *:

female:

Rhinorrhoea (watery mucus discharge from the nose)
Saccadic eye movement (saccadic eye movements are very fast jumps from one eye position to another)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Sleep disorder
Sneezing
Swelling
Tardive dyskinesia (a disorder that involves involuntary movements)
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
Thyroid mass
Abdominal pain upper

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal cancer (cancer of kidney)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Cyst (a closed sac)
Device failure
Diabetes mellitus inadequate control
Flushing (the warm, red condition of human skin)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the common drug interactions of Lodine and Lantus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Aspartate aminotransferase increased
Autoimmune hepatitis
Blood alkaline phosphatase increased
Chest pain
Dizziness
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Flushing (the warm, red condition of human skin)

30-39:

Infection
Pneumonia

40-49:

Flushing (the warm, red condition of human skin)
Pruritus (severe itching of the skin)

50-59:

Fatigue (feeling of tiredness)
Hypersomnia (excessive daytime sleepiness (eds))
Suicidal ideation
Depression
Hallucination, auditory (perceiving sounds without auditory stimulus)
Therapeutic response unexpected
Blood glucose increased
Chest pain
Crying
Dementia (madness)

60+:

Abdominal pain upper
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Anaemia (lack of blood)
Chest discomfort
Chronic kidney disease
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Malaise (a feeling of general discomfort or uneasiness)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain in jaw
Palpitations (feelings or sensations that your heart is pounding or racing)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 25.00%
High Blood Pressure: 5 people, 20.83%
High Blood Cholesterol: 4 people, 16.67%
Type 2 Diabetes: 3 people, 12.50%
Seasonal Affective Disorder (a type of depression that occurs at a certain time of the year, usually in the winter): 3 people, 12.50%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 12.50%
Itching: 3 people, 12.50%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 12.50%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 12.50%
Cardiac Failure Congestive: 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Lodine and Lantus?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously