Lodine and Propulsid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lodine (etodolac) and Propulsid (cisapride monohydrate). Common drug interactions include fatigue among females and eructation among males.

The phase IV clinical study analyzes what interactions people have when they take Lodine and Propulsid. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Lodine?

Lodine has active ingredients of etodolac. It is often used in pain. eHealthMe is studying from 3,846 Lodine users. Check the latest studies of Lodine.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.



On Jul, 08, 2026

27 people who take Lodine and Propulsid together, and have interactions are studied.

Lodine and Propulsid drug interactions.

What are the common drug interactions of Lodine and Propulsid, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  3. Cough
  4. Vomiting
  5. Arthralgia (joint pain)
  6. Chest pain
  7. Dehydration (dryness resulting from the removal of water)
  8. Diarrhoea
  9. Laryngitis (inflammation of the larynx)
  10. Mitral valve incompetence (inefficient heart valve)

male:

  1. Eructation (release of gas from the digestive tract)
  2. Hypotension (abnormally low blood pressure)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Nausea (feeling of having an urge to vomit)
  5. Syncope (loss of consciousness with an inability to maintain postural tone)
  6. Vomiting

What are the common drug interactions of Lodine and Propulsid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Dysfunctional uterine bleeding
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Pain in limb
  4. Pelvic pain
  5. Uterine fibroids (benign growths of the muscle inside the uterus)

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Anxiety
  3. Aortic valve stenosis (narrowing of the aortic valve)
  4. Calcinosis (calcium deposits in any soft tissue)
  5. Cardiac disorder
  6. Chest pain
  7. Headache (pain in head)
  8. Mitral valve incompetence (inefficient heart valve)
  9. Tricuspid valve incompetence (inefficient heart valve)

50-59:

  1. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  2. Hyperglycaemia (high blood sugar)
  3. Hyperlipidaemia (presence of excess lipids in the blood)
  4. Hypertension (high blood pressure)
  5. Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
  6. Myalgia (muscle pain)
  7. Nervousness
  8. Pneumonia
  9. Pruritus (severe itching of the skin)
  10. Pulmonary hypertension (increase in blood pressure in the lung artery)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Syncope (loss of consciousness with an inability to maintain postural tone)
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Viral infection
  6. Cardiac failure
  7. Chest pain
  8. Chest tightness
  9. Dysuria (painful or difficult urination)
  10. Fatigue (feeling of tiredness)

* Approximation only. Some reports may have incomplete information.

Do you take Lodine and Propulsid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lodine and Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lodine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lodine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Propulsid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on etodolac and cisapride monohydrate (the active ingredients of Lodine and Propulsid, respectively), and Lodine and Propulsid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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