Lomotil and Travatan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lomotil (atropine sulfate; diphenoxylate hydrochloride) and Travatan (travoprost). Common drug interactions include dehydration among females and enterocolitis infectious among males.

The phase IV clinical study analyzes what interactions people have when they take Lomotil and Travatan. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Lomotil?

Lomotil has active ingredients of atropine sulfate; diphenoxylate hydrochloride. It is often used in diarrhea. eHealthMe is studying from 19,184 Lomotil users. Check the latest studies of Lomotil.

What is Travatan?

Travatan has active ingredients of travoprost. It is often used in glaucoma. eHealthMe is studying from 13,103 Travatan users. Check the latest studies of Travatan.



On Jul, 16, 2026

41 people who take Lomotil and Travatan together, and have interactions are studied.

Lomotil and Travatan drug interactions.

What are the common drug interactions of Lomotil and Travatan, by gender? *:

female:

  1. Dehydration (dryness resulting from the removal of water)
  2. Eye operation complication
  3. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  4. Intraocular pressure decreased
  5. Muscle spasms (muscle contraction)
  6. Nausea (feeling of having an urge to vomit)
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Oedema peripheral (superficial swelling)
  9. Plasma cell myeloma (cancer that begins in plasma cells)
  10. Abdominal pain

male:

  1. Enterocolitis infectious
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Infusion related reaction
  4. Muscle spasms (muscle contraction)
  5. Platelet count decreased
  6. Urticaria (rash of round, red welts on the skin that itch intensely)
  7. White blood cell count decreased
  8. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  9. Asthenia (weakness)
  10. Back pain

What are the common drug interactions of Lomotil and Travatan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Enterocolitis infectious
  3. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  4. Abdominal pain
  5. Bladder transitional cell carcinoma (types of bladder cancer)
  6. Blood sodium decreased
  7. Clostridial infection (infectious conditions by clostridium bacteria)
  8. Constipation
  9. Cough
  10. Death

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 11 people, 26.83%
  2. High Blood Pressure: 4 people, 9.76%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 9.76%
  4. Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 4 people, 9.76%
  5. Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Lomotil and Travatan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lomotil and Travatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lomotil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Travatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lomotil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Travatan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on atropine sulfate; diphenoxylate hydrochloride and travoprost (the active ingredients of Lomotil and Travatan, respectively), and Lomotil and Travatan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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