Loniten and Optimark drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Loniten (minoxidil) and Optimark (gadoversetamide). Common drug interactions include nephrogenic systemic fibrosis among females.
The phase IV clinical study analyzes what interactions people have when they take Loniten and Optimark. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Loniten?
Loniten has active ingredients of minoxidil. eHealthMe is studying from 363 Loniten users. Check the latest studies of Loniten.
What is Optimark?
Optimark has active ingredients of gadoversetamide. eHealthMe is studying from 3,055 Optimark users. Check the latest studies of Optimark.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
13 people who take Loniten and Optimark together, and have interactions are studied.

What are the common drug interactions of Loniten and Optimark, by gender? *:
female:
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Oedema peripheral (superficial swelling)
- Joint contracture (a permanent shortening of a muscle or joint)
- Joint stiffness
- Mobility decreased (ability to move is reduced)
- Muscular weakness (muscle weakness)
- Pain
- Pain of skin
- Paralysis
- Rash macular (small, flat red spots)
male:
n/a
What are the common drug interactions of Loniten and Optimark, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Oedema peripheral (superficial swelling)
- Joint contracture (a permanent shortening of a muscle or joint)
- Joint stiffness
- Mobility decreased (ability to move is reduced)
- Muscular weakness (muscle weakness)
- Pain
- Pain of skin
- Paralysis
- Rash macular (small, flat red spots)
60+:
n/a
What are the existing conditions these people have? *
- Nuclear Magnetic Resonance Imaging Brain: 12 people, 92.31%
- Diabetes: 6 people, 46.15%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 46.15%
- Anaemia (lack of blood): 6 people, 46.15%
- Chest Pain: 5 people, 38.46%
- Pain: 3 people, 23.08%
* Approximation only. Some reports may have incomplete information.
Do you take Loniten and Optimark?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Loniten and Optimark:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Loniten:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Optimark:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Loniten and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Optimark and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .
- Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on minoxidil and gadoversetamide (the active ingredients of Loniten and Optimark, respectively), and Loniten and Optimark (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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