Loperamide hydrochloride and Alendronic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loperamide hydrochloride (loperamide hydrochloride) and Alendronic acid (alendronate sodium). Common drug interactions include neuropathy peripheral among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Loperamide hydrochloride and Alendronic acid. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Loperamide hydrochloride?

Loperamide hydrochloride has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 10,814 Loperamide hydrochloride users. Check the latest studies of Loperamide hydrochloride.

What is Alendronic acid?

Alendronic acid has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 18,408 Alendronic acid users. Check the latest studies of Alendronic acid.

On Jul, 08, 2026

61 people who take Loperamide hydrochloride and Alendronic acid together, and have interactions are studied.

Loperamide hydrochloride and Alendronic acid drug interactions.

What are the common drug interactions of Loperamide Hydrochloride and Alendronic Acid, by gender? *:

female:

Neuropathy peripheral (surface nerve damage)
Urinary tract infection
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)
Appendicitis (inflammation of the appendix)
Febrile neutropenia (fever with reduced white blood cells)
Affective disorder (mental disorder)
Coma (state of unconsciousness lasting more than six hours)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Large intestine perforation (hole in large intestine)

male:

Drug ineffective
Gastroenteritis staphylococcal (inflammation of stomach and intestine caused by staphylococcal infection)
Agitation (state of anxiety or nervous excitement)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Visual brightness
Visual disturbance

What are the common drug interactions of Loperamide Hydrochloride and Alendronic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Nausea (feeling of having an urge to vomit)

60+:

Lower respiratory tract infection
Mouth ulceration (mouth ulcers)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Large intestine perforation (hole in large intestine)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Somnolence (a state of near-sleep, a strong desire for sleep)
Osteoporotic fracture (fracture due to weak bone)
Appendicitis (inflammation of the appendix)
Febrile neutropenia (fever with reduced white blood cells)
Abdominal pain upper

What are the existing conditions these people have? *

Breast Cancer Metastatic: 28 people, 45.90%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 7 people, 11.48%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 7 people, 11.48%
Enterocolitis Haemorrhagic (bleeding and inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 5 people, 8.20%
Ill-Defined Disorder: 4 people, 6.56%
High Blood Pressure: 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

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