Lopid and Cogentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lopid (gemfibrozil) and Cogentin (benztropine mesylate). Common drug interactions include diabetic complication among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Lopid and Cogentin. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Lopid?

Lopid has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 9,700 Lopid users. Check the latest studies of Lopid.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

On Aug, 09, 2026

35 people who take Lopid and Cogentin together, and have interactions are studied.

What are the common drug interactions of Lopid and Cogentin, by gender? *:

female:

Diabetic complication
Diabetic nephropathy (diabetic kidney disease)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Diarrhoea
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Dizziness
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)
Ear haemorrhage (bleeding from ear)
Ear pain

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 2 diabetes mellitus
Pancreatitis acute (sudden inflammation of pancreas)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Bipolar disorder (mood disorder)
Blood glucose increased
Hyperglycaemia (high blood sugar)
Weight increased
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Lopid and Cogentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Diabetes mellitus inadequate control
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Overdose
Pancreatitis acute (sudden inflammation of pancreas)
Pyrexia (fever)
Rectal haemorrhage (bleeding from anus)
Thermal burn (burn by heat)
Type 2 diabetes mellitus

30-39:

Abnormal loss of weight
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dental caries
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Leukopenia (less number of white blood cells in blood)
Mental retardation severity unspecified (problems with learning and developing severity unspecified)
Palpitations (feelings or sensations that your heart is pounding or racing)
Personality change
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

40-49:

Back injury
Bipolar disorder (mood disorder)
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Blood creatine phosphokinase increased
Cardiac fibrillation (uncontrolled muscle contraction of heart)
Chest pain
Cholecystitis acute (rapid infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Clamminess (moist, sticky, and cold to the touch)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)

50-59:

Chest pain
Schizoaffective disorder (a mental disorder characterized by disordered thought)
Abdominal pain
Abscess oral (abscess in the mouth)
Anxiety
Arthralgia (joint pain)
Back pain
Bipolar disorder (mood disorder)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chills (felling of cold)

60+:

Nausea (feeling of having an urge to vomit)
Cataract (clouding of the lens inside the eye)
Neuropathy peripheral (surface nerve damage)
Renal failure acute (rapid kidney dysfunction)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic complication
Diabetic nephropathy (diabetic kidney disease)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Heart rate increased
Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 12 people, 34.29%
Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 20.00%
Bipolar Disorder (mood disorder): 7 people, 20.00%
Depression: 5 people, 14.29%
Stress And Anxiety: 4 people, 11.43%
Tendon Pain: 2 people, 5.71%
Schizoaffective Disorder Bipolar Type (mental illness featuring schizophrenia and a mood disorder with mania): 2 people, 5.71%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 5.71%
Quit Smoking: 2 people, 5.71%
Parkinsonian Gait (gait exhibited by patients suffering from parkinson's disease): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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