Lopid and Senna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lopid (gemfibrozil) and Senna (senna). Common drug interactions include bone density decreased among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Lopid and Senna. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Lopid?

Lopid has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 9,700 Lopid users. Check the latest studies of Lopid.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

On Aug, 05, 2026

27 people who take Lopid and Senna together, and have interactions are studied.

What are the common drug interactions of Lopid and Senna, by gender? *:

female:

Bone density decreased
Death
Emotional distress
Tooth loss
Anuria (failure of the kidneys to produce urine)
Chills (felling of cold)
Dysuria (painful or difficult urination)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Insomnia (sleeplessness)
Palpitations (feelings or sensations that your heart is pounding or racing)

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Anxiety
Tooth fracture
Asthma
Atelectasis (partial or complete collapse of the lung)
Calculus urinary (stone in urinary system)
Cauda equina syndrome (affecting the bundle of nerve roots)
Diabetic foot
Dyslipidaemia (abnormal amount of lipids)
Hepatic steatosis (fatty liver disease)

What are the common drug interactions of Lopid and Senna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Death
Disturbance in attention
Dizziness
Epistaxis (bleed from the nose)
Feeling hot
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Heart rate increased
Hyperhidrosis (abnormally increased sweating)
Loss of consciousness

50-59:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypersomnia (excessive daytime sleepiness (eds))
Injury
Localised infection (infection at the single location)
Myelopathy (any neurologic deficit related to the spinal cord)
Pneumonia
Pyrexia (fever)
Sleep disorder
Abdominal hernia
Aspartate aminotransferase increased

60+:

Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Pneumonia
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal pain (kidney pain)
Urinary tract infection
Abdominal pain
Acute respiratory failure
Anaemia (lack of blood)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 14.81%
Pain: 4 people, 14.81%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
Type 2 Diabetes: 3 people, 11.11%
Metabolic Disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 2 people, 7.41%
Insomnia (sleeplessness): 2 people, 7.41%
Hypersensitivity: 2 people, 7.41%
Hiv Infection: 2 people, 7.41%
Nausea (feeling of having an urge to vomit): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Lopid and Senna?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously