Lopressor and Diclofenac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lopressor (metoprolol tartrate) and Diclofenac (diclofenac). Common drug interactions include loss of consciousness among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Lopressor and Diclofenac. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Lopressor?

Lopressor has active ingredients of metoprolol tartrate. It is often used in high blood pressure. eHealthMe is studying from 33,152 Lopressor users. Check the latest studies of Lopressor.

What is Diclofenac?

Diclofenac has active ingredients of diclofenac. eHealthMe is studying from 41,319 Diclofenac users. Check the latest studies of Diclofenac.

On Jul, 22, 2026

61 people who take Lopressor and Diclofenac together, and have interactions are studied.

Lopressor and Diclofenac drug interactions.

What are the common drug interactions of Lopressor and Diclofenac, by gender? *:

female:

Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Nervousness
Pain in extremity
Sinusitis (inflammation of sinus)
Swelling
Weight decreased
Weight increased

male:

Blood creatinine increased
Chronic kidney disease
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Tooth disorder (tooth disease)
Renal haematoma (blood collection in kidney)
Abscess limb (limb infection)
Ageusia (loss of taste functions of the tongue)
Alpha 1 foetoprotein decreased
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood chloride decreased

What are the common drug interactions of Lopressor and Diclofenac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dysphagia (a condition in which swallowing is difficult or painful)
Lung neoplasm malignant (cancer tumour of lung)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Tongue disorder (disease of tongue)

40-49:

Diarrhoea
Anaemia (lack of blood)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Vitamin d deficiency
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Acute myocardial infarction (acute heart attack)
Gait disturbance

50-59:

Chondropathy (disease of the cartilage)
Gastrointestinal inflammation (inflammation of stomach and intestine)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Blood creatinine increased
Chronic kidney disease
Emotional distress
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain

60+:

Body temperature decreased
Nasopharyngitis (inflammation of the nasopharynx)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood pressure diastolic increased
Breast pain
Chest discomfort
Dehydration (dryness resulting from the removal of water)
Depression
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 15 people, 24.59%
Joint Pain: 14 people, 22.95%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 16.39%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 16.39%
Drowsiness: 8 people, 13.11%
Pain: 6 people, 9.84%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 9.84%
Stress And Anxiety: 4 people, 6.56%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

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