Lopressor and Moduretic 5-50 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lopressor (metoprolol tartrate) and Moduretic 5-50 (amiloride hydrochloride; hydrochlorothiazide). Common drug interactions include hyperkalaemia among females and dysphagia among males.

The phase IV clinical study analyzes what interactions people have when they take Lopressor and Moduretic 5-50. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lopressor?

Lopressor has active ingredients of metoprolol tartrate. It is often used in high blood pressure. eHealthMe is studying from 33,152 Lopressor users. Check the latest studies of Lopressor.

What is Moduretic 5-50?

Moduretic 5-50 has active ingredients of amiloride hydrochloride; hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 3,224 Moduretic 5-50 users. Check the latest studies of Moduretic 5-50.

On Jul, 19, 2026

18 people who take Lopressor and Moduretic 5-50 together, and have interactions are studied.

Lopressor and Moduretic 5-50 drug interactions.

What are the common drug interactions of Lopressor and Moduretic 5-50, by gender? *:

female:

Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Malaise (a feeling of general discomfort or uneasiness)
Melaena (the passage of black, tarry stools)
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Asthenia (weakness)
Autoimmune thrombocytopenia (isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia)
Blood cholesterol increased
Circulatory collapse

male:

Dysphagia (a condition in which swallowing is difficult or painful)
Cellulitis (infection under the skin)
Hemiparesis (weakness on one side of the body)
Lung infection
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neurodermatitis (a skin disorder characterized by long lasting itching and scratching)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Pruritus (severe itching of the skin)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)

What are the common drug interactions of Lopressor and Moduretic 5-50, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Blood cholesterol increased
Cellulitis (infection under the skin)
Cerebral atrophy (decrement in size of brain)
Chest pain
Circulatory collapse
Clostridium colitis (inflammation of colon by clostridium difficile bacteria infection)
Colitis (inflammation of colon)
Colitis pseudomembranous (antibiotic-associated diarrhoea)

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 1 person, 5.56%
Osteoporosis (bones weak and more likely to break): 1 person, 5.56%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.56%
Gastric Ulcer (stomach ulcer): 1 person, 5.56%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 5.56%
Asthma: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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