Loprox and Lamisil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loprox (ciclopirox) and Lamisil (terbinafine hydrochloride). Common drug interactions include beta 2 microglobulin increased among females and body temperature decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Loprox and Lamisil. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Loprox?

Loprox has active ingredients of ciclopirox. eHealthMe is studying from 618 Loprox users. Check the latest studies of Loprox.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

On Jul, 11, 2026

49 people who take Loprox and Lamisil together, and have interactions are studied.

What are the common drug interactions of Loprox and Lamisil, by gender? *:

female:

Beta 2 microglobulin increased
Blood calcium decreased
Blood glucose increased
Blood lactate dehydrogenase increased
Blood triglycerides increased
Body temperature increased
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

Body temperature decreased
Pruritus (severe itching of the skin)
Skin exfoliation (removal of the oldest dead skin cells)
Skin lesion
Skin plaque (red, scaly patches to appear on the skin)
Transient acantholytic dermatosis (a skin condition that causes the appearance of small, red spots on chest and back)
Urticaria (rash of round, red welts on the skin that itch intensely)
Abdominal pain
Injection site reaction
Stress

What are the common drug interactions of Loprox and Lamisil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Diarrhoea
Fall
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Pruritus (severe itching of the skin)
Sweating increased (excess sweating)
Tremor (trembling or shaking movements in one or more parts of your body)

30-39:

Abdominal pain upper
Acute respiratory distress syndrome
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anisocytosis (patient's red blood cells are of unequal size)
Anxiety
Asthenia (weakness)
Back pain
Beta 2 microglobulin increased
Blood calcium decreased
Blood glucose increased

40-49:

Arthralgia (joint pain)
Dysphagia (a condition in which swallowing is difficult or painful)
Emotional distress
Gait disturbance
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Oedema peripheral (superficial swelling)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pyrexia (fever)
Abdominal discomfort
Abdominal distension

50-59:

Phlebitis (inflammation of the walls of a vein)
Urinary tract infection bacterial
Wound
Visual disturbance
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
Vitreous floaters (spots before the eyes)
Body temperature decreased
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Discomfort
Drug ineffective

60+:

Malaise (a feeling of general discomfort or uneasiness)
Abscess (pus)
Constipation
Death
Inflammation
Lethargy (tiredness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nasopharyngitis (inflammation of the nasopharynx)
Pain of skin
Abdominal distension

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 11 people, 22.45%
Urticaria (rash of round, red welts on the skin that itch intensely): 8 people, 16.33%
Joint Injury: 7 people, 14.29%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 4 people, 8.16%
Nail Tinea (fungal infection of nail): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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