Lopurin and Abelcet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lopurin (allopurinol) and Abelcet (amphotericin b). Common drug interactions include diarrhoea among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Lopurin and Abelcet. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

What is Abelcet?

Abelcet has active ingredients of amphotericin b. eHealthMe is studying from 853 Abelcet users. Check the latest studies of Abelcet.



On Jul, 15, 2026

36 people who take Lopurin and Abelcet together, and have interactions are studied.

Lopurin and Abelcet drug interactions.

What are the common drug interactions of Lopurin and Abelcet, by gender? *:

female:

  1. Diarrhoea
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Herpes virus infection
  4. Hypotension (abnormally low blood pressure)
  5. Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
  6. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  7. Metrorrhagia (uterine bleeding at irregular intervals)
  8. Mucosal inflammation (infection of mucous membrane)
  9. Nausea (feeling of having an urge to vomit)
  10. Pericardial effusion (fluid around the heart)

male:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Hyperbilirubinaemia (excess of bilirubin in the blood)
  3. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  4. Haemorrhage (bleeding)
  5. Pneumonia
  6. Renal failure (kidney dysfunction)
  7. Blood bilirubin increased
  8. Confusion
  9. Delirium (wild excitement)
  10. Diarrhoea

What are the common drug interactions of Lopurin and Abelcet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Confusion
  2. Delirium (wild excitement)
  3. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  4. Haemoglobin decreased
  5. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  6. Hepatitis (inflammation of the liver)
  7. Hyperbilirubinaemia (excess of bilirubin in the blood)
  8. Hypoxia (low oxygen in tissues)
  9. Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
  10. Rectal bleeding (bleeding from rectum)

40-49:

  1. Blood creatinine increased
  2. Cardiac tamponade (fluid accumulates in heart covering)
  3. Diarrhoea
  4. Febrile neutropenia (fever with reduced white blood cells)
  5. Herpes virus infection
  6. Metrorrhagia (uterine bleeding at irregular intervals)
  7. Mucosal inflammation (infection of mucous membrane)
  8. Nausea (feeling of having an urge to vomit)
  9. Pericardial effusion (fluid around the heart)
  10. Urinary tract infection enterococcal

50-59:

  1. Encephalopathy (functioning of the brain is affected by some agent or condition)
  2. Hepatorenal failure (decrease in kidney function in a person with a severe liver disorder)
  3. Respiratory alkalosis (elevated blood ph due to excess breathing)
  4. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  5. Anaemia (lack of blood)
  6. Blood bilirubin increased
  7. Blood creatinine increased
  8. Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
  9. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  10. Cardiomyopathy (weakening of the heart muscle)

60+:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Hyperbilirubinaemia (excess of bilirubin in the blood)
  3. Confusional state
  4. Depressed level of consciousness
  5. Diarrhoea
  6. Enterococcal infection
  7. Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
  8. Eye infection
  9. Fluid overload (too much fluid in the blood)
  10. Hepatosplenomegaly (enlargement of both the liver and the spleen)

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 14 people, 38.89%
  2. Vaginal Bleeding: 6 people, 16.67%
  3. Constipation: 6 people, 16.67%
  4. Pain: 5 people, 13.89%
  5. Fever: 5 people, 13.89%
  6. Abdominal Pain: 5 people, 13.89%
  7. Thrombocytopenia (decrease of platelets in blood): 4 people, 11.11%
  8. Nausea (feeling of having an urge to vomit): 4 people, 11.11%
  9. Hypokalemia (low potassium): 4 people, 11.11%
  10. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 4 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Lopurin and Abelcet?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lopurin and Abelcet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lopurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Abelcet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lopurin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abelcet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol and amphotericin b (the active ingredients of Lopurin and Abelcet, respectively), and Lopurin and Abelcet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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