Lopurin and Echinacea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lopurin (allopurinol) and Echinacea (echinacea). Common drug interactions include ageusia among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Lopurin and Echinacea. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

What is Echinacea?

Echinacea has active ingredients of echinacea. It is often used in immune response. eHealthMe is studying from 1,930 Echinacea users. Check the latest studies of Echinacea.



On Jul, 09, 2026

83 people who take Lopurin and Echinacea together, and have interactions are studied.

Lopurin and Echinacea drug interactions.

What are the common drug interactions of Lopurin and Echinacea, by gender? *:

female:

  1. Ageusia (loss of taste functions of the tongue)
  2. Anaemia (lack of blood)
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. Blood pressure increased
  6. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  7. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  8. Crying
  9. Death
  10. Delusional disorder, unspecified type

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Vomiting
  3. Headache (pain in head)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Abdominal pain upper
  6. Adverse drug reaction
  7. Agitation (state of anxiety or nervous excitement)
  8. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  9. Ataxia (loss of full control of bodily movements)
  10. Back pain

What are the common drug interactions of Lopurin and Echinacea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Crying
  2. Dehydration (dryness resulting from the removal of water)
  3. Delusional disorder, unspecified type
  4. Depressed mood
  5. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  6. Feeding disorder (when children refuse to eat certain food groups)
  7. Helminthic infection (worms infection)
  8. Hypotension (abnormally low blood pressure)
  9. Infection parasitic
  10. Intestinal obstruction

60+:

  1. Thrombosis (formation of a blood clot inside a blood vessel)
  2. Infusion site thrombosis
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Abdominal pain upper
  5. Adverse drug reaction
  6. Agitation (state of anxiety or nervous excitement)
  7. Anaemia (lack of blood)
  8. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  9. Ataxia (loss of full control of bodily movements)
  10. Back pain

What are the existing conditions these people have? *

  1. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 28 people, 33.73%
  2. Primary Myelofibrosis (primary disorder of the bone marrow): 10 people, 12.05%
  3. Pain: 6 people, 7.23%
  4. High Blood Cholesterol: 6 people, 7.23%
  5. Hepatitis C: 5 people, 6.02%
  6. Diabetes: 5 people, 6.02%
  7. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

Do you take Lopurin and Echinacea?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lopurin and Echinacea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lopurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Echinacea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lopurin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Echinacea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol and echinacea (the active ingredients of Lopurin and Echinacea, respectively), and Lopurin and Echinacea (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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