Lopurin and Ingrezza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lopurin (allopurinol) and Ingrezza (valbenazine tosylate). Common drug interactions include somnolence among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Lopurin and Ingrezza. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

What is Ingrezza?

Ingrezza has active ingredients of valbenazine tosylate. eHealthMe is studying from 23,666 Ingrezza users. Check the latest studies of Ingrezza.

On Aug, 09, 2026

57 people who take Lopurin and Ingrezza together, and have interactions are studied.

What are the common drug interactions of Lopurin and Ingrezza, by gender? *:

female:

Somnolence (a state of near-sleep, a strong desire for sleep)
Asthenia (weakness)
Fungal cystitis (fungal infection of bladder)
Memory impairment
Lethargy (tiredness)
Urinary tract infection
Anaemia (lack of blood)
Dry mouth
Fatigue (feeling of tiredness)
Gingival erosion (gum ulcer)

male:

Fatigue (feeling of tiredness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Balance disorder
Confusional state
Dizziness
Drooling (drop saliva uncontrollably from the mouth)
Dysphonia (speech disorder attributable to a disorder of phonation)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)

What are the common drug interactions of Lopurin and Ingrezza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dystonia (abnormal muscle tone)

50-59:

Asthenia (weakness)
Fungal cystitis (fungal infection of bladder)
Memory impairment
Confusional state
Renal impairment (severely reduced kidney function)
Somnolence (a state of near-sleep, a strong desire for sleep)
Urinary tract infection
Cystitis (inflammation of the wall of the bladder)
Agitation (state of anxiety or nervous excitement)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)

60+:

Somnolence (a state of near-sleep, a strong desire for sleep)
Lethargy (tiredness)
Dementia (madness)
Drooling (drop saliva uncontrollably from the mouth)
Dysphagia (a condition in which swallowing is difficult or painful)
Fluid retention (an abnormal accumulation of fluid in the blood)
Insomnia (sleeplessness)
Joint stiffness
Lip swelling
Miliaria (a skin disease marked by small and itchy rashes)

What are the existing conditions these people have? *

Tardive Dyskinesia (a disorder that involves involuntary movements): 48 people, 84.21%
High Blood Pressure: 6 people, 10.53%
Pain: 5 people, 8.77%
Stress And Anxiety: 3 people, 5.26%
High Blood Cholesterol: 3 people, 5.26%
Heart Disease: 3 people, 5.26%
Depression: 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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