Loratadine and Eucrisa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loratadine (loratadine) and Eucrisa (crisaborole). Common drug interactions include sleep disorder among females and dermatitis atopic among males.

The phase IV clinical study analyzes what interactions people have when they take Loratadine and Eucrisa. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Loratadine?

Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,315 Loratadine users. Check the latest studies of Loratadine.

What is Eucrisa?

Eucrisa has active ingredients of crisaborole. eHealthMe is studying from 9,900 Eucrisa users. Check the latest studies of Eucrisa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

66 people who take Loratadine and Eucrisa together, and have interactions are studied.

Loratadine and Eucrisa drug interactions.

What are the common drug interactions of Loratadine and Eucrisa, by gender? *:

female:

  1. Sleep disorder
  2. Status asthmaticus (a asthma attack not responds to regular medicines)
  3. Swelling
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  5. Therapeutic response decreased (less preventive response)
  6. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  7. Rash
  8. Arthralgia (joint pain)
  9. Cough
  10. Drug ineffective

male:

  1. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  2. Injection site mass
  3. Drug ineffective
  4. Dysphonia (speech disorder attributable to a disorder of phonation)
  5. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  6. Foreign body sensation in eyes (feeling of something in eye)
  7. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  8. Hypersensitivity
  9. Injection site pain
  10. Injection site swelling

What are the common drug interactions of Loratadine and Eucrisa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Burning sensation
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Dry skin
  4. Head injury
  5. Injection site pain
  6. Injection site rash
  7. Insomnia (sleeplessness)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Pain
  10. Pruritus (severe itching of the skin)

10-19:

  1. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  2. Arthralgia (joint pain)
  3. Alopecia (absence of hair from areas of the body)
  4. Back pain
  5. Dry skin
  6. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  7. Headache (pain in head)
  8. Hypersensitivity
  9. Influenza
  10. Nerve compression

20-29:

  1. Injection site mass
  2. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  3. Dry eye (lack of adequate tears)
  4. Cough
  5. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  6. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  7. Influenza
  8. Malaise (a feeling of general discomfort or uneasiness)

30-39:

  1. Pneumonia

40-49:

  1. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  2. Rash
  3. Conjunctivitis (pink eye)
  4. Abdominal distension
  5. Coeliac artery compression syndrome (abdominal pain related to compression of the celiac artery)
  6. Foreign body sensation in eyes (feeling of something in eye)
  7. Hepatic steatosis (fatty liver disease)
  8. Hypertension (high blood pressure)
  9. Insomnia (sleeplessness)
  10. Liver injury

50-59:

  1. Drug ineffective
  2. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  3. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  4. Erythema (redness of the skin)
  5. Infection
  6. Injection site reaction
  7. Injection site swelling
  8. Peripheral swelling
  9. Rash
  10. Rash macular (small, flat red spots)

60+:

  1. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  2. Lymphadenopathy (disease or enlargement of lymph nodes)
  3. Headache (pain in head)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Muscle spasms (muscle contraction)
  6. Nausea (feeling of having an urge to vomit)
  7. Respiratory disorder (respiratory disease)
  8. Sinusitis (inflammation of sinus)
  9. Upper respiratory tract infection
  10. Vomiting

What are the existing conditions these people have? *

  1. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 48 people, 72.73%
  2. Asthma: 6 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Loratadine and Eucrisa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Loratadine and Eucrisa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loratadine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Eucrisa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loratadine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Eucrisa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loratadine and crisaborole (the active ingredients of Loratadine and Eucrisa, respectively), and Loratadine and Eucrisa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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