Loratadine and Flector drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loratadine (loratadine) and Flector (diclofenac epolamine). Common drug interactions include night sweats among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Loratadine and Flector. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Loratadine?

Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,314 Loratadine users. Check the latest studies of Loratadine.

What is Flector?

Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 5,112 Flector users. Check the latest studies of Flector.



On Aug, 08, 2026

26 people who take Loratadine and Flector together, and have interactions are studied.

Loratadine and Flector drug interactions.

What are the common drug interactions of Loratadine and Flector, by gender? *:

female:

  1. Night sweats (sweating in night)
  2. Nightmare (unpleasant dream)
  3. Oedema peripheral (superficial swelling)
  4. Pain in extremity
  5. Patellofemoral pain syndrome (pain in the front of the knee)
  6. Pelvic pain
  7. Peripheral swelling
  8. Personality disorder
  9. Plantar fasciitis (painful inflammatory process of the plantar fascia)
  10. Rash

male:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Emotional distress
  4. Faecal incontinence (a lack of control over passing stool)
  5. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
  6. Gait disturbance
  7. Haemorrhage (bleeding)
  8. Nephrogenic anaemia (anaemia due to kidney disease)
  9. Rectal haemorrhage (bleeding from anus)
  10. Renal failure (kidney dysfunction)

What are the common drug interactions of Loratadine and Flector, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Alanine aminotransferase increased
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Aspartate aminotransferase increased
  5. Blood alkaline phosphatase increased
  6. Blood bilirubin increased
  7. Bone density decreased
  8. Bone pain
  9. Chronic kidney disease
  10. Drug resistance (reduction in effectiveness of a drug)

50-59:

  1. Dyskinesia (abnormality or impairment of voluntary movement)
  2. Overweight
  3. Pneumonia
  4. Renal injury (kidney injury)
  5. Chronic kidney disease
  6. Diplopia (double vision)
  7. Drug hypersensitivity
  8. Dry eye (lack of adequate tears)
  9. Dry mouth
  10. Dysphagia (a condition in which swallowing is difficult or painful)

60+:

  1. Chronic kidney disease
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Constipation
  4. Diarrhoea
  5. Faecal incontinence (a lack of control over passing stool)
  6. Fibromyalgia (a long-term condition which causes pain all over the body)
  7. Gait disturbance
  8. Haemorrhage (bleeding)
  9. Injection site pain
  10. Injection site swelling

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 30.77%
  2. High Blood Cholesterol: 7 people, 26.92%
  3. High Blood Pressure: 6 people, 23.08%
  4. Sleep Disorder: 5 people, 19.23%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 15.38%
  6. Cardiac Disorder: 4 people, 15.38%
  7. Nausea (feeling of having an urge to vomit): 4 people, 15.38%
  8. Depression: 4 people, 15.38%
  9. Inflammation: 4 people, 15.38%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Loratadine and Flector:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loratadine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flector:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loratadine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flector and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loratadine and diclofenac epolamine (the active ingredients of Loratadine and Flector, respectively), and Loratadine and Flector (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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