Loratadine and Harvoni drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loratadine (loratadine) and Harvoni (ledipasvir; sofosbuvir). Common drug interactions include rhabdomyolysis among females and alcohol withdrawal syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Loratadine and Harvoni. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Loratadine?

Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,314 Loratadine users. Check the latest studies of Loratadine.

What is Harvoni?

Harvoni has active ingredients of ledipasvir; sofosbuvir. eHealthMe is studying from 19,858 Harvoni users. Check the latest studies of Harvoni.

On Jul, 10, 2026

38 people who take Loratadine and Harvoni together, and have interactions are studied.

Loratadine and Harvoni drug interactions.

What are the common drug interactions of Loratadine and Harvoni, by gender? *:

female:

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Somnolence (a state of near-sleep, a strong desire for sleep)
Swelling
Urinary tract infection
Vision blurred
Headache (pain in head)
Chronic kidney disease
Pyrexia (fever)
Alopecia (absence of hair from areas of the body)

male:

Alcohol withdrawal syndrome
Anaemia (lack of blood)
Pain
Depression
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hypoxia (low oxygen in tissues)
Mobility decreased (ability to move is reduced)
Osteopenia (a condition where bone mineral density is lower than normal)
Substance abuse
Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Loratadine and Harvoni, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Lacrimation increased
Papilloedema (optic disc swelling)
Substance abuse
Vision blurred
Alcohol withdrawal syndrome
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Asthenia (weakness)
Burning sensation
Eye pruritus (eye itching)
Headache (pain in head)

40-49:

Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Back pain
Chest pain
Chills (felling of cold)
Chronic kidney disease
Drug ineffective
Dysstasia (difficulty in standing)
Emotional distress

50-59:

Drug ineffective
Fatigue (feeling of tiredness)
Hepatitis c
Alopecia (absence of hair from areas of the body)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bacterial infection
Blood creatinine increased
Cellulitis (infection under the skin)
Chronic kidney disease

60+:

Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Thrombocytopenia (decrease of platelets in blood)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Postictal state
Abdominal pain
Alanine aminotransferase increased
Ascites (accumulation of fluid in the abdominal cavity)
Aspartate aminotransferase increased
Death

What are the existing conditions these people have? *

Hepatitis C: 25 people, 65.79%
Hiv Infection: 5 people, 13.16%
Pain: 4 people, 10.53%
Hypersensitivity: 3 people, 7.89%
Diabetes: 3 people, 7.89%
Infection: 2 people, 5.26%
High Blood Pressure: 2 people, 5.26%
Gout (uric acid crystals building up in the body): 2 people, 5.26%
Constipation: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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