Loratadine and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loratadine (loratadine) and Soliris (eculizumab). Common drug interactions include rash among females and haemolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Loratadine and Soliris. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Loratadine?

Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,314 Loratadine users. Check the latest studies of Loratadine.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

On Jul, 15, 2026

60 people who take Loratadine and Soliris together, and have interactions are studied.

Loratadine and Soliris drug interactions.

What are the common drug interactions of Loratadine and Soliris, by gender? *:

female:

Rash
Urinary tract infection
Urticaria (rash of round, red welts on the skin that itch intensely)
Blood pressure increased
Peripheral swelling
Fatigue (feeling of tiredness)
Pelvic pain
Arthralgia (joint pain)
Pyrexia (fever)
Back pain

male:

Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Meningitis meningococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
Cardiac tamponade (fluid accumulates in heart covering)
Delusion (a false belief or opinion)
Depression
Enterococcal infection
Escherichia infection (bacterial infection by escherichia coli)
Fall
Fatigue (feeling of tiredness)
Fungal infection

What are the common drug interactions of Loratadine and Soliris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Fatigue (feeling of tiredness)
Migraine (headache)
Proteinuria (presence of protein in the urine)
Asthma
Blood creatinine increased
Dyspnoea exertional (breathlessness or shortness of breath)

20-29:

Abdominal pain
Allergic cough
Cough
Drug hypersensitivity
Dysphonia (speech disorder attributable to a disorder of phonation)
Haemoglobinuria (the presence of free haemoglobin in the urine)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Hypersensitivity
Pruritus generalised (generalized itching)
Skin lesion

30-39:

Thrombocytopenia (decrease of platelets in blood)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Rhinorrhoea (watery mucus discharge from the nose)
Vomiting
Back pain
Haemoglobin decreased
Bacteraemia (presence of bacteria in the blood)
Chest pain
Clostridial infection (infectious conditions by clostridium bacteria)

40-49:

Ear discomfort
Fluid retention (an abnormal accumulation of fluid in the blood)
Muscle spasms (muscle contraction)
Precancerous cells present
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

50-59:

Blood pressure increased
Peripheral swelling
Fatigue (feeling of tiredness)
Feeling jittery
Headache (pain in head)
Muscular weakness (muscle weakness)

60+:

Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Essential thrombocythaemia (chronic blood cancer)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Infusion site haematoma (localized swelling filled with blood at infusion site)
Muscular weakness (muscle weakness)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Cholecystitis (infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 18 people, 30.00%
Hypersensitivity: 12 people, 20.00%
High Blood Pressure: 11 people, 18.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 11.67%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 6 people, 10.00%
Pain: 4 people, 6.67%
Migraine (headache): 4 people, 6.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 6.67%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Loratadine and Soliris?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously