Loraz and Apriso drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Apriso (mesalamine). Common drug interactions include gastric ulcer among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Apriso. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.

What is Apriso?

Apriso has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 3,439 Apriso users. Check the latest studies of Apriso.

On Jul, 13, 2026

55 people who take Loraz and Apriso together, and have interactions are studied.

What are the common drug interactions of Loraz and Apriso, by gender? *:

female:

Gastric ulcer (stomach ulcer)
Gingival pain (gum pain)
Haematocrit decreased
Haemoglobin decreased
Head injury
Hyperhidrosis (abnormally increased sweating)
Injection site bruising
Joint injury
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)

male:

Pain
Emotional distress
Blood calcium decreased
Chronic kidney disease
Decreased activity
Foot fracture
Fracture
Grip strength decreased
Hand fracture
Multiple fractures

What are the common drug interactions of Loraz and Apriso, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Biliary colic
Cholecystitis acute (rapid infection of gallbladder)
Diarrhoea
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Nausea (feeling of having an urge to vomit)
Pancreatitis (inflammation of pancreas)
Injection site anaesthesia
Injection site haemorrhage (bleeding from injection site)
Injection site pain

40-49:

Abdominal pain
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dizziness
Fatigue (feeling of tiredness)
Gastric ulcer (stomach ulcer)
Injection site pain
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Nausea (feeling of having an urge to vomit)
Vomiting
Chronic kidney disease

50-59:

Pain
Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Renal failure (kidney dysfunction)
Chronic kidney disease
Osteopenia (a condition where bone mineral density is lower than normal)
Blood calcium decreased
Decreased activity
Foot fracture
Fracture

60+:

Diarrhoea
Bruxism (habitual grinding of the teeth, typically during sleep)
Retinal injury (injury to retina)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Headache (pain in head)
Myalgia (muscle pain)
Paranasal sinus discomfort
Rhinorrhoea (watery mucus discharge from the nose)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Age-related macular degeneration

What are the existing conditions these people have? *

Depression: 23 people, 41.82%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 19 people, 34.55%
Pain: 17 people, 30.91%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 21.82%
High Blood Cholesterol: 12 people, 21.82%
Diarrhea: 12 people, 21.82%
Insomnia (sleeplessness): 12 people, 21.82%
High Blood Pressure: 11 people, 20.00%
Asthma: 10 people, 18.18%
Sleep Disorder: 10 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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