Loraz and Betapace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Betapace (sotalol hydrochloride). Common drug interactions include oesophagitis among females and coronary artery disease among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Betapace. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.

What is Betapace?

Betapace has active ingredients of sotalol hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,899 Betapace users. Check the latest studies of Betapace.

On Jul, 29, 2026

68 people who take Loraz and Betapace together, and have interactions are studied.

What are the common drug interactions of Loraz and Betapace, by gender? *:

female:

Oesophagitis (inflammation of oesophagus)
Oral candidiasis (fungal infection of mouth)
Respiratory rate decreased (less breathing rate/min)
Anaemia of chronic disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Atrioventricular block complete (heart block complete)
Blood magnesium decreased
Chest discomfort
Coronary artery stenosis (narrowing of coronary artery)
Dehydration (dryness resulting from the removal of water)

male:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Neuropathy peripheral (surface nerve damage)
Fractured sacrum
General physical health deterioration (weak health status)
Neuralgia (pain in one or more nerves)
Anaemia (lack of blood)
Cardiac arrest
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Marrow hyperplasia (increased bone marrow)
Bone pain

What are the common drug interactions of Loraz and Betapace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal infection
Abdominal pain upper
Acidosis (build-up of carbon dioxide in the blood)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Asthenia (weakness)
Back pain
Blood cholesterol increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchopleural fistula
Cardiac failure congestive

30-39:

n/a

40-49:

n/a

50-59:

Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Asthenia (weakness)
Blood glucose decreased
Blood glucose increased
Blood thyroid stimulating hormone decreased
Cardiac failure congestive
Chest discomfort
Chest pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetic nephropathy (diabetic kidney disease)

60+:

Pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Bone pain
Fractured sacrum
General physical health deterioration (weak health status)
Neuralgia (pain in one or more nerves)
Psoriasis (immune-mediated disease that affects the skin)
Tobacco user
Anaemia (lack of blood)
Cardiac arrest

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 25 people, 36.76%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 24 people, 35.29%
Stable Angina (a constant chest pain): 23 people, 33.82%
Depression: 23 people, 33.82%
Arrhythmias (irregular heartbeat): 23 people, 33.82%
Pain: 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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