Loraz and Caduet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Caduet (amlodipine besylate; atorvastatin calcium). Common drug interactions include chest pain among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Caduet. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.

What is Caduet?

Caduet has active ingredients of amlodipine besylate; atorvastatin calcium. It is often used in high blood pressure. eHealthMe is studying from 5,157 Caduet users. Check the latest studies of Caduet.

On Jul, 11, 2026

70 people who take Loraz and Caduet together, and have interactions are studied.

What are the common drug interactions of Loraz and Caduet, by gender? *:

female:

Chest pain
Dyspnoea exertional (breathlessness or shortness of breath)
Hypertensive heart disease
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Arrhythmia (irregular heartbeat)
Bradycardia (abnormally slow heart action)
Cardiac murmur (an heart sound in valve abnormality)
Chronic kidney disease
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

male:

Arthralgia (joint pain)
Pain
Cardiomyopathy (weakening of the heart muscle)
Cyst (a closed sac)
Cytomegalovirus infection
Decreased interest
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)

What are the common drug interactions of Loraz and Caduet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Confusional state
Overdose
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Abdominal discomfort
Abdominal distension
Anaemia (lack of blood)
Arthralgia (joint pain)
Asthenia (weakness)
Blood magnesium decreased
Blood sodium decreased
Bone disorder

50-59:

Ligament rupture (tear in ligament)
Myalgia (muscle pain)
Speech disorder
Weight decreased
Hypoglycaemia (deficiency of glucose in the bloodstream)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diabetes mellitus inadequate control
Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Neuropathy peripheral (surface nerve damage)

60+:

Renal failure (kidney dysfunction)
Chronic kidney disease
Dyspnoea exertional (breathlessness or shortness of breath)
Hypertensive heart disease
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Interstitial lung disease
Arrhythmia (irregular heartbeat)
Bradycardia (abnormally slow heart action)
Cardiac murmur (an heart sound in valve abnormality)
Eye haemorrhage (bleeding in the eye)

What are the existing conditions these people have? *

Pain: 15 people, 21.43%
High Blood Cholesterol: 12 people, 17.14%
Depression: 12 people, 17.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 14.29%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 12.86%
Diabetes: 8 people, 11.43%
Urination - Excessive Volume: 6 people, 8.57%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 8.57%
Inflammation: 6 people, 8.57%
Infection: 6 people, 8.57%

* Approximation only. Some reports may have incomplete information.

Do you take Loraz and Caduet?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously