Loraz and Cerebyx drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Loraz (lorazepam) and Cerebyx (fosphenytoin sodium). Common drug interactions include disseminated intravascular coagulation among females and flushing among males.
The phase IV clinical study analyzes what interactions people have when they take Loraz and Cerebyx. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Loraz?
Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.
What is Cerebyx?
Cerebyx has active ingredients of fosphenytoin sodium. eHealthMe is studying from 515 Cerebyx users. Check the latest studies of Cerebyx.
21 people who take Loraz and Cerebyx together, and have interactions are studied.

What are the common drug interactions of Loraz and Cerebyx, by gender? *:
female:
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Drug hypersensitivity
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Hepatic necrosis (large portions of liver die off due to severe liver disease)
- Leukopenia (less number of white blood cells in blood)
- Multi-organ failure (multisystem organ failure)
- Renal tubular necrosis (death of kidney tubules)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
male:
- Flushing (the warm, red condition of human skin)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Pruritus (severe itching of the skin)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
What are the common drug interactions of Loraz and Cerebyx, by age (0-1 to 60+)? *:
0-1:
- Blood phosphate increased
- Bradycardia (abnormally slow heart action)
- Cardiac arrest
- Drug toxicity
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
- Superior sagittal sinus thrombosis (blood clot in the dural venous sinuses, which drain blood from the brain)
- Vasogenic cerebral oedema (increase in brain water)
- Vision blurred
- Cerebral haemorrhage (bleeding within the brain)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
50-59:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Hepatic necrosis (large portions of liver die off due to severe liver disease)
- Leukopenia (less number of white blood cells in blood)
- Multi-organ failure (multisystem organ failure)
- Renal tubular necrosis (death of kidney tubules)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
- Hepatic failure (liver failure)
- Lymphopenia (an abnormally low level of lymphocytes in the blood)
60+:
- Blindness transient (sudden loss of vision)
What are the existing conditions these people have? *
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 13 people, 61.90%
- High Blood Pressure: 8 people, 38.10%
* Approximation only. Some reports may have incomplete information.
Do you take Loraz and Cerebyx?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Loraz and Cerebyx:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Loraz:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cerebyx:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Loraz and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cerebyx and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lorazepam and fosphenytoin sodium (the active ingredients of Loraz and Cerebyx, respectively), and Loraz and Cerebyx (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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