Loraz and Fazaclo odt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Fazaclo odt (clozapine). Common drug interactions include death among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Fazaclo odt. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.

What is Fazaclo odt?

Fazaclo odt has active ingredients of clozapine. eHealthMe is studying from 728 Fazaclo odt users. Check the latest studies of Fazaclo odt.



On Jul, 12, 2026

26 people who take Loraz and Fazaclo odt together, and have interactions are studied.

Loraz and Fazaclo odt drug interactions.

What are the common drug interactions of Loraz and Fazaclo Odt, by gender? *:

female:

  1. Death
  2. Agitation (state of anxiety or nervous excitement)
  3. Balance disorder
  4. Cardiac failure
  5. Cardiac failure congestive
  6. Fall
  7. Weight decreased
  8. Aggression
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  10. Back pain

male:

  1. Death
  2. Acute respiratory distress syndrome
  3. Essential hypertension (primary hypertension)
  4. Exhibitionism (practice of deliberately behaving so as to attract attention)
  5. Haematemesis (vomiting of blood)
  6. Intestinal obstruction
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  8. Oedema mouth (swelling of mouth)
  9. Oral mucosal erythema (redness of the mucous membrane of mouth)
  10. Pneumonia

What are the common drug interactions of Loraz and Fazaclo Odt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Increased appetite
  2. Oedema mouth (swelling of mouth)
  3. Oral mucosal erythema (redness of the mucous membrane of mouth)
  4. Psychotic disorder
  5. Swollen tongue (swelling of tongue)
  6. Weight increased

30-39:

n/a

40-49:

  1. Back pain
  2. Cardiac failure
  3. Dizziness
  4. Dyspepsia (indigestion)
  5. Exhibitionism (practice of deliberately behaving so as to attract attention)
  6. Psychiatric decompensation (worsening of symptoms to the state of a serious mental disorder)
  7. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)

50-59:

  1. Acute respiratory distress syndrome
  2. Acute respiratory failure
  3. Agitation (state of anxiety or nervous excitement)
  4. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  5. Weight decreased
  6. Aggression
  7. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  8. Balance disorder
  9. Cerebral haemorrhage (bleeding within the brain)
  10. Death

60+:

  1. Death
  2. Cardiac failure congestive
  3. Peripheral swelling
  4. Pneumonia
  5. Respiratory distress (difficulty in breathing)
  6. Sudden death
  7. Swelling face
  8. Unresponsive to stimuli
  9. Arteriosclerosis (thickening and hardening of arteries)
  10. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)

What are the existing conditions these people have? *

  1. Dementia (madness): 5 people, 19.23%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 15.38%
  3. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 3 people, 11.54%
  4. Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Loraz and Fazaclo odt?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Loraz and Fazaclo odt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loraz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fazaclo odt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loraz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fazaclo odt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lorazepam and clozapine (the active ingredients of Loraz and Fazaclo odt, respectively), and Loraz and Fazaclo odt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: