Loraz and Istodax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Istodax (romidepsin). Common drug interactions include neutropenia among females and disseminated cytomegaloviral infection among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Istodax. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.

What is Istodax?

Istodax has active ingredients of romidepsin. eHealthMe is studying from 1,054 Istodax users. Check the latest studies of Istodax.

On Jul, 14, 2026

14 people who take Loraz and Istodax together, and have interactions are studied.

What are the common drug interactions of Loraz and Istodax, by gender? *:

female:

Neutropenia (an abnormally low number of neutrophils)
Pleural effusion (water on the lungs)
Renal failure acute (rapid kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Fall
Febrile neutropenia (fever with reduced white blood cells)
General physical health deterioration (weak health status)
Glomerular filtration rate decreased
Muscular weakness (muscle weakness)

male:

Disseminated cytomegaloviral infection (group of herpes viruses infection)
Enterococcal infection
Intracranial haematoma (intracranial localized swelling filled with blood)
Respiratory failure (inadequate gas exchange by the respiratory system)
Thrombocytopenia (decrease of platelets in blood)
Injection site extravasation (flow of (blood or lymph) from injection site)
Platelet count decreased

What are the common drug interactions of Loraz and Istodax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Atelectasis (partial or complete collapse of the lung)
Pleural effusion (water on the lungs)

40-49:

n/a

50-59:

Platelet count decreased

60+:

Thrombocytopenia (decrease of platelets in blood)
Respiratory failure (inadequate gas exchange by the respiratory system)
Fall
Febrile neutropenia (fever with reduced white blood cells)
General physical health deterioration (weak health status)
Glomerular filtration rate decreased
Injection site extravasation (flow of (blood or lymph) from injection site)
Muscular weakness (muscle weakness)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pain

What are the existing conditions these people have? *

T-Cell Lymphoma (a blood cell cancer): 3 people, 21.43%
Nausea (feeling of having an urge to vomit): 3 people, 21.43%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 14.29%
Breast Cancer Metastatic: 2 people, 14.29%
Peripheral T-Cell Lymphoma Unspecified (peripheral t-cell cancer unspecified): 2 people, 14.29%
Pain: 2 people, 14.29%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 14.29%
Nausea And Vomiting: 2 people, 14.29%
Diabetes: 1 person, 7.14%
Fatigue (feeling of tiredness): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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