Loraz and Kineret drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Kineret (anakinra). Common drug interactions include pyrexia among females and left ventricular hypertrophy among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Kineret. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,695 Loraz users. Check the latest studies of Loraz.

What is Kineret?

Kineret has active ingredients of anakinra. It is often used in rheumatoid arthritis. eHealthMe is studying from 11,120 Kineret users. Check the latest studies of Kineret.



On Aug, 12, 2026

47 people who take Loraz and Kineret together, and have interactions are studied.

Loraz and Kineret drug interactions.

What are the common drug interactions of Loraz and Kineret, by gender? *:

female:

  1. Pyrexia (fever)
  2. Spinal osteoarthritis (joint cartilage loss in spine)
  3. Vaginal candidiasis (vaginal fungal infection)
  4. Vaginal cyst
  5. Visual disturbance
  6. Vomiting
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. White blood cell count decreased
  9. Balance disorder
  10. Bronchial hyperreactivity

male:

  1. Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
  2. Abdominal infection
  3. Blood calcium decreased
  4. Blood chloride increased
  5. Blood creatinine decreased
  6. Blood fibrinogen decreased
  7. Blood glucose increased
  8. Blood lactate dehydrogenase increased
  9. Blood magnesium increased
  10. Blood phosphorus decreased

What are the common drug interactions of Loraz and Kineret, by age (0-1 to 60+)? *:

0-1:

  1. Abdominal infection
  2. Activated partial thromboplastin time prolonged
  3. Alanine aminotransferase increased
  4. Ammonia decreased
  5. Anaemia (lack of blood)
  6. Anion gap increased
  7. Aspartate aminotransferase increased
  8. Blast cell count increased
  9. Blood albumin decreased
  10. Blood calcium decreased

2-9:

  1. Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)

10-19:

n/a

20-29:

  1. Injection site urticaria (rash of round, red welts on the skin at injection site)

30-39:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Abdominal pain
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. C-reactive protein increased
  6. Chest pain
  7. Drug ineffective
  8. Fatigue (feeling of tiredness)
  9. Head injury
  10. Injection site reaction

40-49:

  1. Interstitial lung disease
  2. Erectile dysfunction
  3. Fungal infection
  4. Headache (pain in head)
  5. Injection site pain
  6. Injection site pruritus (severe itching at injection site)
  7. Injection site urticaria (rash of round, red welts on the skin at injection site)
  8. Pain
  9. Peripheral neuropathy (damage to nerves of the peripheral nervous system)
  10. Rash

50-59:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Tuberculosis (a bacterial infection by mycobacterium tuberculosis)
  3. Klebsiella infection
  4. Leg ulcer (excl varicose) (leg ulcer without varicose vein)
  5. Night sweats (sweating in night)
  6. Pleural effusion (water on the lungs)
  7. Urinary tract infection
  8. Drug effect decreased
  9. Dyspnoea (difficult or laboured respiration)
  10. Fatigue (feeling of tiredness)

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Nausea (feeling of having an urge to vomit)
  3. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  4. Drug ineffective
  5. Joint swelling
  6. Lung nodule (solid, raised areas in lung)
  7. Peripheral swelling
  8. Pyelonephritis (inflammation of kidney caused by bacteria)
  9. Pyrexia (fever)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Loraz and Kineret:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loraz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kineret:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loraz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kineret and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam and anakinra (the active ingredients of Loraz and Kineret, respectively), and Loraz and Kineret (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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