Loraz and Nph insulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Nph insulin (insulin susp isophane beef). Common drug interactions include arthralgia among females and cytokine release syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Nph insulin. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.

What is Nph insulin?

Nph insulin has active ingredients of insulin susp isophane beef. It is often used in diabetes. eHealthMe is studying from 1,871 Nph insulin users. Check the latest studies of Nph insulin.



On Jul, 26, 2026

47 people who take Loraz and Nph insulin together, and have interactions are studied.

Loraz and Nph insulin drug interactions.

What are the common drug interactions of Loraz and Nph Insulin, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Asthma
  3. Atelectasis (partial or complete collapse of the lung)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Back pain
  6. Blood magnesium decreased
  7. Blood pressure immeasurable
  8. Blood sodium decreased
  9. Bone cyst
  10. Bone disorder

male:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  2. Pyrexia (fever)
  3. Pneumonia bacterial (pneumonia associated with bacterial infection)
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  5. Delirium (wild excitement)
  6. Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
  7. Thrombocytopenia (decrease of platelets in blood)
  8. Pneumonia
  9. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  10. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)

What are the common drug interactions of Loraz and Nph Insulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Death

30-39:

  1. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  2. Migraine (headache)
  3. Type 2 diabetes mellitus
  4. Asthma
  5. Cold sweat
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

40-49:

  1. Anaemia (lack of blood)
  2. Dyspnoea (difficult or laboured respiration)
  3. Ear infection
  4. Hysterectomy
  5. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  6. Sinusitis (inflammation of sinus)
  7. Uterine cyst
  8. Uterine enlargement
  9. Vaginal haemorrhage (vaginal bleeding)

50-59:

  1. Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
  2. Acute respiratory failure
  3. Anaemia (lack of blood)
  4. Ataxia (loss of full control of bodily movements)
  5. Ear infection
  6. Eye injury
  7. Fall
  8. Headache (pain in head)
  9. Hypoxia (low oxygen in tissues)
  10. Hysterectomy

60+:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  2. Diarrhoea
  3. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  4. Hypotension (abnormally low blood pressure)
  5. Acute respiratory failure
  6. Alanine aminotransferase increased
  7. Aspartate aminotransferase increased
  8. Blood lactic acid increased
  9. Cardiac failure
  10. Drug ineffective

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 8 people, 17.02%
  2. Type 2 Diabetes: 6 people, 12.77%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 12.77%
  4. Depression: 5 people, 10.64%
  5. Urinary Tract Infection: 5 people, 10.64%
  6. Agitation (state of anxiety or nervous excitement): 4 people, 8.51%
  7. Insomnia (sleeplessness): 4 people, 8.51%
  8. Pain: 4 people, 8.51%
  9. Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 4 people, 8.51%
  10. Dyspnea (difficult or laboured breathing): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

Do you take Loraz and Nph insulin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Loraz and Nph insulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loraz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nph insulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loraz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nph insulin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam and insulin susp isophane beef (the active ingredients of Loraz and Nph insulin, respectively), and Loraz and Nph insulin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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