Loraz and Percodan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Percodan (aspirin; oxycodone hydrochloride; oxycodone terephthalate). Common drug interactions include weight decreased among females and haemorrhagic stroke among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Percodan. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.

What is Percodan?

Percodan has active ingredients of aspirin; oxycodone hydrochloride; oxycodone terephthalate. It is often used in pain. eHealthMe is studying from 12,885 Percodan users. Check the latest studies of Percodan.

On Jul, 12, 2026

30 people who take Loraz and Percodan together, and have interactions are studied.

What are the common drug interactions of Loraz and Percodan, by gender? *:

female:

Weight decreased
Drug ineffective
Breast cancer
Hyperhidrosis (abnormally increased sweating)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Neuralgia (pain in one or more nerves)
Abdominal pain
Abdominal pain upper
Abnormal behaviour

male:

Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Constipation
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Drug dependence
Dyspnoea (difficult or laboured respiration)
Fall
Femur fracture
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Headache (pain in head)

What are the common drug interactions of Loraz and Percodan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dependence
Respiratory distress (difficulty in breathing)

30-39:

Sudden death unexplained
Abdominal pain
Drug dependence
Haematemesis (vomiting of blood)
Kidney infection
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Nausea (feeling of having an urge to vomit)
Pyelonephritis (inflammation of kidney caused by bacteria)
Pyrexia (fever)
Urine discolouration

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Abdominal pain upper
Abnormal dreams
Back pain
Cardiac failure congestive
Confusion
Dizziness
Drug ineffective
Eructation (release of gas from the digestive tract)
Fatigue (feeling of tiredness)

50-59:

Cerebral haemorrhage (bleeding within the brain)
Abnormal behaviour
Aggression
Bipolar disorder (mood disorder)
Blood pressure increased
Chest pain
Constipation
Cystitis (inflammation of the wall of the bladder)
Drug abuser
Drug dependence

60+:

Antisocial behaviour
Constipation
Suicidal ideation
Abnormal dreams
Fall
Femur fracture
Hip fracture
Vomiting

What are the existing conditions these people have? *

Hepatitis C: 9 people, 30.00%
Depression: 8 people, 26.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 20.00%
Indigestion: 5 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 16.67%
Sleep Disorder: 4 people, 13.33%
Quit Smoking: 4 people, 13.33%
High Blood Pressure: 4 people, 13.33%
Anaemia (lack of blood): 4 people, 13.33%
Muscle Aches (muscle pain): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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