Lorcet-hd and Doxycycline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lorcet-hd (acetaminophen; hydrocodone bitartrate) and Doxycycline (doxycycline hyclate). Common drug interactions include weight increased among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Lorcet-hd and Doxycycline. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Lorcet-hd?

Lorcet-hd has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 2,221 Lorcet-hd users. Check the latest studies of Lorcet-hd.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

On Aug, 07, 2026

36 people who take Lorcet-hd and Doxycycline together, and have interactions are studied.

Lorcet-hd and Doxycycline drug interactions.

What are the common drug interactions of Lorcet-Hd and Doxycycline, by gender? *:

female:

Weight increased
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Renal failure chronic (long lasting kidney dysfunction)
Hyperhidrosis (abnormally increased sweating)
Neck pain
Abdominal pain

male:

Depression
Drug dependence
Nausea (feeling of having an urge to vomit)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Synovitis (inflammation of the synovial membrane)
Vomiting
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Arthralgia (joint pain)
Back injury
Cough

What are the common drug interactions of Lorcet-Hd and Doxycycline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac disorder
Cardiac failure congestive
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Joint injury
Migraine (headache)
Thrombosis (formation of a blood clot inside a blood vessel)
Type 1 diabetes mellitus
Viral cardiomyopathy (weakness in the muscle of the heart due to viral infection)

30-39:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Depression
Hypoaesthesia (reduced sense of touch or sensation)
Suicidal ideation
Urinary tract infection
Agitation (state of anxiety or nervous excitement)
Drug abuser
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cardiac disorder
Difficulty in walking

40-49:

Depression
Drug dependence
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Rash
Anxiety
Chest pain
Dehydration (dryness resulting from the removal of water)
Drug abuser
Gastroenteritis (inflammation of stomach and intestine)

50-59:

Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
Constipation
Dehydration (dryness resulting from the removal of water)
Depression
Drug dependence
Heart rate increased
Heart valve incompetence (heart's valves do not work correctly)
Hyperhidrosis (abnormally increased sweating)
Hypokalaemia (low potassium)
Ileus (a painful obstruction of the ileum or other part of the intestine)

60+:

Hypertension (high blood pressure)
Neuropathy peripheral (surface nerve damage)
Renal failure chronic (long lasting kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperkalaemia (damage to or disease of the kidney)
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Bradycardia (abnormally slow heart action)
Angina pectoris (chest pain due to ischemia of the heart muscle)

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 19.44%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 8.33%
Menopause (end of monthly cycles in women): 3 people, 8.33%
Joint Pain: 3 people, 8.33%
Stress And Anxiety: 2 people, 5.56%
Hallucination, Auditory (perceiving sounds without auditory stimulus): 2 people, 5.56%
Depression: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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