Lorcet-hd and Lopurin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lorcet-hd (acetaminophen; hydrocodone bitartrate) and Lopurin (allopurinol). Common drug interactions include obsessive-compulsive disorder among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Lorcet-hd and Lopurin. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Lorcet-hd?

Lorcet-hd has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 2,221 Lorcet-hd users. Check the latest studies of Lorcet-hd.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

On Jul, 19, 2026

37 people who take Lorcet-hd and Lopurin together, and have interactions are studied.

Lorcet-hd and Lopurin drug interactions.

What are the common drug interactions of Lorcet-Hd and Lopurin, by gender? *:

female:

Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pitting oedema (skin discoloration)
Proteinuria (presence of protein in the urine)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Wheezing (a high-pitched whistling sound made while you breath)
Anxiety
Arthralgia (joint pain)
Carotid artery aneurysm (a bulging or ballooning in the wall of a blood vessel)

male:

Dizziness
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Chronic obstructive airways disease
Dysuria (painful or difficult urination)
Hyperglycaemia (high blood sugar)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Breast mass
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cellulitis (infection under the skin)
Drug dependence

What are the common drug interactions of Lorcet-Hd and Lopurin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness
Memory impairment
Muscle spasms (muscle contraction)
Pain in extremity
Phlebitis (inflammation of the walls of a vein)
Facial palsy (paralysis of face nerve)
Anxiety
Insomnia (sleeplessness)
Viith nerve paralysis

40-49:

Candidiasis (candidiasis or thrush is a fungal infection)
Cardiac disorder
Chills (felling of cold)
Cholecystitis chronic (long lasting infection of gallbladder)
Citrobacter infection (infection by citrobacter (bacteria))
Constipation
Decreased appetite
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dyspnoea (difficult or laboured respiration)

50-59:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Leukocytosis (increased white blood cells)
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Asthenia (weakness)
Blood glucose increased
Blood uric acid increased
Chest pain
Diarrhoea
Drug ineffective

60+:

Asthenia (weakness)
Febrile neutropenia (fever with reduced white blood cells)
Breast mass
Cardiac failure
Cellulitis (infection under the skin)
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysuria (painful or difficult urination)
Electrocardiogram qt prolonged
Gastritis (inflammation of stomach)

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 24.32%
High Blood Cholesterol: 7 people, 18.92%
Stress And Anxiety: 6 people, 16.22%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 10.81%
Insomnia (sleeplessness): 4 people, 10.81%
Depression: 4 people, 10.81%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 8.11%
Therapeutic Response Decreased (less preventive response): 2 people, 5.41%
Muscle Spasms (muscle contraction): 2 people, 5.41%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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