Lorcet-hd and Mobic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lorcet-hd (acetaminophen; hydrocodone bitartrate) and Mobic (meloxicam). Common drug interactions include bursitis among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Lorcet-hd and Mobic. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Lorcet-hd?

Lorcet-hd has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 2,221 Lorcet-hd users. Check the latest studies of Lorcet-hd.

What is Mobic?

Mobic has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 26,684 Mobic users. Check the latest studies of Mobic.



On Jul, 10, 2026

37 people who take Lorcet-hd and Mobic together, and have interactions are studied.

Lorcet-hd and Mobic drug interactions.

What are the common drug interactions of Lorcet-Hd and Mobic, by gender? *:

female:

  1. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Constipation
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Dehydration (dryness resulting from the removal of water)
  6. Drug hypersensitivity
  7. Drug ineffective
  8. Forearm fracture (fracture in between wrist to elbow)
  9. Haematuria (presence of blood in urine)
  10. Hand fracture

male:

  1. Depression
  2. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  3. Deformity (disfigurement)
  4. Dyskinesia (abnormality or impairment of voluntary movement)
  5. Excessive eye blinking (excessive blinking is dry eyes)
  6. Insomnia (sleeplessness)
  7. Muscle spasms (muscle contraction)
  8. Personality change
  9. Post-traumatic stress disorder
  10. Agitation (state of anxiety or nervous excitement)

What are the common drug interactions of Lorcet-Hd and Mobic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cardiac disorder
  2. Cardiac failure congestive
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Diarrhoea
  5. Drug abuser
  6. Drug dependence
  7. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  8. Fall
  9. Hyperhidrosis (abnormally increased sweating)
  10. Hypoglycaemia (deficiency of glucose in the bloodstream)

30-39:

  1. Drug ineffective
  2. Dry mouth
  3. Emotional distress
  4. Heart rate increased
  5. Nervousness
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Throat tightness
  8. Abdominal distension
  9. Abdominal pain
  10. Abdominal tenderness

40-49:

  1. Oropharyngeal pain
  2. Palpitations (feelings or sensations that your heart is pounding or racing)
  3. Acute myocardial infarction (acute heart attack)
  4. Angina pectoris (chest pain due to ischemia of the heart muscle)
  5. Arthralgia (joint pain)
  6. Asthma
  7. Atelectasis (partial or complete collapse of the lung)
  8. Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
  9. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  10. Cardiomegaly (increased size of heart than normal)

50-59:

  1. Hyperglycaemia (high blood sugar)
  2. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  3. Asthma
  4. Blood pressure increased
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  7. Depression
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Cystitis (inflammation of the wall of the bladder)
  2. Bone pain
  3. Forearm fracture (fracture in between wrist to elbow)
  4. Haematuria (presence of blood in urine)
  5. Hand fracture
  6. Headache (pain in head)
  7. Hypersensitivity
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  9. International normalised ratio increased
  10. Laceration (tearing of soft body tissue)

What are the existing conditions these people have? *

  1. Depression: 9 people, 24.32%
  2. Stress And Anxiety: 6 people, 16.22%
  3. Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 13.51%
  4. Oral Candidiasis (fungal infection of mouth): 5 people, 13.51%
  5. Back Pain: 5 people, 13.51%
  6. Sleep Apnea Syndrome: 4 people, 10.81%
  7. Sinus Disorder (disease of sinus): 3 people, 8.11%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 8.11%
  9. High Blood Pressure: 3 people, 8.11%
  10. Diabetes: 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lorcet-hd and Mobic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lorcet-hd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mobic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lorcet-hd and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mobic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate and meloxicam (the active ingredients of Lorcet-hd and Mobic, respectively), and Lorcet-hd and Mobic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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